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Seneste peer-review'ede publikationer ved MBG

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Jensen, R. K., Miehe, M., Gandini, R., Jørgensen, M. H., Spillner, E. & Andersen, G. R. (2026). Cryo-EM Structure of FcεRI Bound IgE Reveals Multiple Defined Conformations of the Fab-Fc Hinge. Allergy: European Journal of Allergy and Clinical Immunology, 81(6), 2047-2058. https://doi.org/10.1111/all.70132

Goto, T., Andersen, K. R., Bamba, M., Sato, S., Sugawara, M., Minamisawa, K., Kawaguchi, M., Stougaard, J. & Kawaharada, Y. (2026). Cyclophilin A-mediated cis/trans isomerization modulates RIN4 to control intracellular rhizobial infection in legumes. New Phytologist, 250(6), 3932-3945. https://doi.org/10.1111/nph.71147

Harazin, A., Reinert, L. S., Alam, P., Hoy, L., Marnow, A. B., Nielsen, J., Lorentzen, A., Otzen, D. E., Paludan, S. R. & Nielsen, M. S. (2026). Double-Stranded DNA Sensing cGAS-STING Immune Signaling in a Rat Co-Culture Model of the Blood-Brain Barrier. Cell Biochemistry and Function, 44(6), e70240. Artikel e70240. https://doi.org/10.1002/cbf.70240

Menaceur Vandenbroucke, C., Scavenius, C. & Hayashi, Y. (2026). EV-SPEC: Decoding the Spatial Proteomic Signature of the Extracellular Vesicle Corona. Journal of Extracellular Biology, 5(6), Artikel e70151. https://doi.org/10.1002/jex2.70151

Authier, F., Esperon-Abril, I., Coquelin, K. S., Skoven, C. S., Eskildsen, S. F., Ondruskova, N., Ferenbach, A. T., Thomsen, J. S., Hansen, B. & van Aalten, D. M. F. (2026). Genetic Rescue of Pathogenic O-GlcNAc Dyshomeostasis Associated with Microcephaly and Motor Deficits. eNeuro , 13(6), Artikel ENEURO.0453-25.2026. https://doi.org/10.1523/ENEURO.0453-25.2026

Kristjánsdóttir, N., Thorsen, K., Birkbak, N. J. & Dyrskjøt, L. (2026). Immune profiling of T cells: A comparative analysis of single-cell TCR sequencing using 10X Genomics and Parse Biosciences platforms. Biochemistry and Biophysics Reports, 46, Artikel 102592. https://doi.org/10.1016/j.bbrep.2026.102592

Lennartsson, C., Kyriakidou, P., Nielsen, M. L., Olsen, J. V., Cox, J. & Hendriks, I. A. (2026). Improved Peptide Search for Identification of SUMO and Sequence-Based Modifiers, in MaxSBM. Molecular & Cellular Proteomics : MCP, 25(6), Artikel 101589. https://doi.org/10.1016/j.mcpro.2026.101589

Adam, L., Molenkamp, W. H., Nowak, J. S., Farzadfard, A., Gaarthuis, K., Kumar, R., Nielsen, J., Otzen, D. E., Johansson, J. & Abelein, A. (2026). Mechanism-selective inhibition of α-synuclein aggregation by the chaperone-like BRICHOS domain. The Journal of Biological Chemistry, 302(6), 113117. Artikel 113117. https://doi.org/10.1016/j.jbc.2026.113117

Talay, A., Belikov, A. V., To, P. K. P., Alfatemi, H. H., Alon, U., Deelen, J., Ewald, C. Y., Gems, D., Gorbunova, V., Gruber, J., Hägg, S., Hemming, J., Horvath, S., Kaya, A., Lewis, C. J., Maier, A. B., Marinova, M. B., Pawelec, G., Peleg, S. ... de Magalhães, J. P. (2026). Open problems in ageing science: a roadmap for biogerontology. GeroScience, 48(3), 3351-3360. https://doi.org/10.1007/s11357-025-01964-4

Gierlich, S. A., Jayakody, T. B., Augustine, S. M., Liu, H., Jääskeläinen, M., Vaisalu, T., Snowdon, R. J. & Andersen, S. U. (2026). Progress and Challenges in Faba Bean Genetic Engineering. Legume Science, 8(2), Artikel e70123. https://doi.org/10.1002/leg3.70123

Stambler, I., Tietz-Latza, A., Schumacher, B., Geiger, H., Morrison, H., Tüscher, O., Fuellen, G., Meisel, R., Simm, A., Pfeiffer, A., Steinhage, A., Popa-Wagner, A., Wagner, W., Cornely, O., Krause, M., Mitrou, G., Kyriazis, M., Scheibye-Knudsen, M., Rattan, S. ... Gonos, E. S. (2026). The need to increase support for healthy ageing and longevity research in the EU by establishing a Coordination and Support Programme on Healthy Ageing and Longevity. Mechanisms of Ageing and Development, 231, Artikel 112187. https://doi.org/10.1016/j.mad.2026.112187

Marquart Løber, I. M., Ward, L. J., Elmsjö, A., Söderberg, C., Villesen, P., Nielsen, K. L. & Green, H. (2026). Human-to-Rat Validation of PMI Biomarkers: A Bidirectional Cross-Species Metabolomics Study Reveals Asymmetric Translation. Analytical Chemistry, 98(20), 14883-14890. https://doi.org/10.1021/acs.analchem.6c00202

Birkbak, N. J., TRACERx Consortium, TRACERx EVO Consortium & PEACE Consortium (2026). Evolutionary characterization of lung cancer metastasis. Nature, 653(8115), 911-922. https://doi.org/10.1038/s41586-026-10428-4

Demaegd, K. C., Kool, L., Baindoor, S., Donovan, P. D., Su, J., Westeneng, H. J., van Eijk, R. P. A., Geoghegan, G., Perez Morrissey, E., Halang, L., Poesen, K., Masrori, P., Gibriel, H. A. Y., Jirström, E., Venø, M. T., Kjems, J., Hardiman, O., Veldink, J. H., Kenna, K. ... van Es, M. A. (2026). Small RNA sequencing identifies serum tDR-1:34-Gly-GCC tiRNA levels as a biomarker for survival in amyotrophic lateral sclerosis. iScience, 29(5), Artikel 115636. https://doi.org/10.1016/j.isci.2026.115636

Djavani-Tabrizi, I., Lindkvist, T. T., Otzen, D. E. & Nielsen, S. B. (2026). When motion slows: intrinsic photophysics of thioflavin T and X cations at cryogenic temperatures. Physical Chemistry Chemical Physics, 28(18), 11181-11186. https://doi.org/10.1039/d6cp00731g

Nakajima, R., Yamamoto, S., Kawamura, Y. K., Kitazawa, T., Kimura, M. & Kitazawa, Y. (2026). Design, Synthesis, and Evaluation of an Ammonium-Terminated Superchaotropic Boron Cluster: Effects on the Transmembrane Delivery of Neutral and Charged Cargos. Inorganic Chemistry, 65(18), 9728-9733. https://doi.org/10.1021/acs.inorgchem.5c05467

Carneiro, I. S. M., Pedrosa, L. R. R., Corrêa, A. C. R., Soares, B. G. C., Rocha, L. S. O., Leal, L. C. P., Passos-Monteiro, E. & Krejcová, L. V. (2026). Dance therapy improves the joint range of motion in people with Parkinson’s disease: an essay with the Baila Parkinson method. Brazilian Journal of Motor Behavior, 20(1), Artikel e536. https://doi.org/10.20338/bjmb.v20i1.526

Lorentzen, J., Fruergaard, M. U., Lukácsi, S., Jørgensen, M. H., van Veghel, T. L. G., Jensen, R. K., Pietrzak-Lichwa, K. J., Bajtay, Z., Hořejší, V., Flygaard, R. K., Vorselen, D., Mortensen, S. A. & Andersen, G. R. (2026). Three cryo-EM structures of complement C3d-bound α_Mβ₂ reveal an unexpected layer of dynamics for αI-containing integrin receptors. Science Advances, 12(19), Artikel eaea7241. https://doi.org/10.1126/sciadv.aea7241

Winther, K. G., Schneider, J., Haas, G., Christensen, A. H., Goyal, S., Luo, W., Wei, Z., Liu, J., Kjøge, K., Enghild, J. J., Meignin, C., Silverman, N., Cai, H., Imler, J. L. & Hartmann, R. (2026). FADD is recruited to activated STING oligomers to initiate caspase-mediated NF-κB activation in Drosophila melanogaster. EMBO Journal, 45(9), 2965-2990. https://doi.org/10.1038/s44318-026-00761-9

Golbek, T. W., Rasmussen, M. H., Bregnhøj, M., Boesen, T., Drace, T., Faase, R., Baio, J. E. & Weidner, T. (2026). Binding and orientation of ice nucleating proteins on hydrophilic and hydrophobic surfaces probed by photoelectron spectroscopies. Biointerphases, 21(3), Artikel 031002. https://doi.org/10.1116/6.0005223

Al-Momani, S. S., Ramsbottom, K., Collins, A., Boswell, E., Hendriks, I. A., Nielsen, M. L., Vertegaal, A. C. O., Hay, R. T., Sun, Z., Riverol, Y. P., Bowler-Barnett, E. H., Martin, M. J., Fan, J., Sadanandom, A., Deutsch, E. W., Vizcaíno, J. A. & Jones, A. R. (2026). A Landscape Analysis of Human SUMOylation. Molecular & Cellular Proteomics : MCP, 25(5), 101571. Artikel 101571. https://doi.org/10.1016/j.mcpro.2026.101571

Faber, A. H., Bataillon, T. & Ehlers, B. K. (2026). Climate-Driven Convergence of Chemical Ecotypes in Mediterranean Lamiaceae. Journal of Biogeography, 53(5), Artikel e70247. https://doi.org/10.1111/jbi.70247

Walpole, S., Santiago-Vela, M. I., Birkedal, U., Hong, Z., Ros, X. B. D., van Overeem Hansen, T. & Wadt, K. A. W. (2026). Functional Analysis and Clinical Data Reclassify the DICER1 c.4206+1G>C Variant, Leading to Exon 22 Skipping, as Likely Pathogenic. Clinical Genetics, 109(5), 931-936. https://doi.org/10.1111/cge.70110

De Dios Andres, P., Garg, A., Alam, R., Westensee, I. N., Kjaergaard, M. & Städler, B. (2026). Transmembrane Condensation in Albumin-Loaded Giant Vesicles Induced by an Intrinsically Disordered Protein. ChemSystemsChem, 8(3), Artikel e00076. https://doi.org/10.1002/syst.202500076

Aliakbari, F., Rahmani, M., Marzookian, K., Boroujeni, N. N., Alikhanian, A., Ghasemi, F., Otzen, D. E. & Morshedi, D. (2026). Exosomes as Advanced Nanocarriers: Overcoming the Blood-Brain Barrier for Targeted Therapeutic Delivery in Neurodegenerative Diseases. Current drug delivery. Advance online publication. https://doi.org/10.2174/0115672018430706251211094801

Bernatz, S., Prudente, V., Pai, S., Attermann, A. K., Di Federico, A., Rowan, A., Veeriah, S., Dyrskjøt, L., Nürnberg, L., Alessi, J. V., Ott, P. A., Sharon, E., Hackshaw, A., McGranahan, N., Abbosh, C., Mak, R. H., Bitterman, D., Awad, M., Ricciuti, B. ... Aerts, H. J. W. L. (2026). Thymic health and immunotherapy outcomes in patients with cancer. Nature, 652(8111), 995-1003. https://doi.org/10.1038/s41586-026-10243-x

Bernatz, S., Prudente, V., Pai, S., Attermann, A. K., Cao, Y., Chen, J., Lyass, A., Foldyna, B., Nürnberg, L., Bressem, K., Abbosh, C., Swanton, C., Jamal-Hanjani, M., Lu, M. T., Murabito, J. M., Lunetta, K. L., Birkbak, N. J. & Aerts, H. J. W. L. (2026). Thymic health consequences in adults. Nature, 652(8111), 986-994. https://doi.org/10.1038/s41586-026-10242-y

Vinther, S. C., Resag, A., Le, K. T. T., Zelle-Rieser, C. C., Strandt, H., Malle, M. G., Christiansen, S. H., Del Frari, B., Stigger, T., Schilling, B., Wohlfarth, J., Thiel, S., Valero, J., Stoitzner, P. & Kjems, J. (2026). Targeting Langerhans cells using a modular mannosylated nucleic acid-based vaccine platform. Journal of Controlled Release, 392, 114741. Artikel 114741. https://doi.org/10.1016/j.jconrel.2026.114741

Vasilevsky, N. A., Toro, S., Matentzoglu, N., Flack, J. E., Mullen, K. R., Hegde, H., Gehrke, S., Whetzel, P. L., Shwetar, Y., Harris, N. L., Ngu, M. S., Alyea, G. L., Kane, M. S., Roncaglia, P., Sid, E., Thaxton, C. L., Wood, V., Abraham, R. S., Achatz, M. I. ... Haendel, M. A. (2026). Mondo: integrating disease terminology across communities. Genetics, 232(4). https://doi.org/10.1093/genetics/iyaf215

Mabruk, Z., Bullock, E., Xiao, X., Guo, J., Zhu, X., Gómez-Cuadrado, L., Oxvig, C., Mallon, E., Ammar, A., Malty, A., Pennel, K., Edwards, J. & Brunton, V. G. (2026). High Expression of PAPP-A Predicts Poor Outcomes in Oestrogen Receptor-Positive Breast Cancer Patients. Cancer Medicine, 15(4), e71815. Artikel e71815. https://doi.org/10.1002/cam4.71815

Hopkinson, A. T., Wilson, A. M., Pitfield, J., Muiña, A. T., Rácz, R., Mifsud, D. V., Herczku, P., Lakatos, G., Sulik, B., Juhász, Z., Biri, S., McCullough, R. W., Mason, N. J., Scavenius, C., Hornekær, L. & Ioppolo, S. (2026). An interstellar energetic and non-aqueous pathway to peptide formation. Nature Astronomy, 10(4), 531-539. https://doi.org/10.1038/s41550-025-02765-7

Rast, J. E., Rosso, A. L., James, B. D., Underwood, J. F. G., Bergstedt, J., Ahlqvist, V. H., Grove, J., Fang, F., Goldstein, N. D., Vivanti, G., Levine, S. Z., Nordström, A., Schendel, D., Lyall, K., Nordström, P., Ballin, M., Stafford, J., Naj, A. C., Lee, B. K. & LEGENNDS Consortium (2026). Association of neurodevelopmental conditions with Alzheimer's disease and related dementias and Parkinson's disease. The Journals of Gerontology. Series A: Biological Sciences & Medical Sciences, 81(4), Artikel glaf281. https://doi.org/10.1093/gerona/glaf281

Graham, R., Wain, B. H., Clark, R. A., Bemmer, V. L., Borin, G. P., Avilan, L., Rudge, E. M., Lahive, C. W., Shaver, M. P. & Pickford, A. R. (2026). Enhanced enzymatic hydrolysis of pretreated polyester textile at high solids loading through fusion with a carbohydrate binding module. Bioresource Technology, 446, Artikel 134174. https://doi.org/10.1016/j.biortech.2026.134174

Lildballe, D. L., Huno, M. R., Ridder, L. O. R., Balle, C. M., Drue, S. O., Berglund, A., Dunø, M., Bak, E. N., Viuff, M. H., Rasmussen, L. S. & Gravholt, C. H. (2026). Genetic diagnosis of CYP21A2-related CAH: adaptive sampling long-read sequencing is an accurate and scalable solution. European Journal of Human Genetics, 34(4), 535-542. https://doi.org/10.1038/s41431-026-02019-8

Rattan, S. (2026). Lifespan stops at death, but when does healthspan stop? Biogerontology, 27(2), 78. Artikel 78. https://doi.org/10.1007/s10522-026-10424-1

Czyżewski, S., Søndergaard, S. A., Molnár, Á. P., Kerr, M. R., Kristensen, J. A., Atkinson, J., Trepel, J., Sykut, M., Radzikowski, P., Termansen, S. S., Wałach, K., Pearce, E. A., Pang, S. E. H., Zając, B., Bergman, J., Thomassen, E. S., Mungi, N., Fløjgaard, C., Ejrnæs, R. ... Svenning, J. C. (2026). Revisiting Europe's temperate forests: Palaeoecological evidence for an herbivory-driven woodland-grassland mosaic biome. Biological Conservation, 316, Artikel 111749. https://doi.org/10.1016/j.biocon.2026.111749

Kats, P., Zhou, X., Wiebe, J., Zeymer, O., Baruch, P., Taft, M. H., Reinke, P. Y. A., Günther, S., Meents, A., Hartmann, R., Manstein, D. J. & Fedorov, R. (2026). The Enzymatic Mechanism of OAS: How Metal Ions and Quantum Effects Help Activate Innate Immunity. ACS Omega, 11(16), 24250-24268. https://doi.org/10.1021/acsomega.5c13236

Zhang, Y., Pilati, D., Dong, M. & Howard, K. A. (2026). The interaction of PD-1/PD-L1 and its inhibition by anti-PD-L1 antibody at the single-molecule level. FEBS Letters, 600(8), 1237-1247. https://doi.org/10.1002/1873-3468.70245

Rezi, C. K., Doganli, C., Aslanyan, M. G., Chamlali, M., Mary, B., Callesen, N. L., Abu-Khesha, R. R. K., Diwan, G. D., Russell, R. B., Lorentzen, E., Boldt, K., Roepman, R., Larsen, L. A. & Pedersen, L. B. (2026). ZDHHC5 interacts physically and functionally with DLG1 at primary cilia and regulates ciliary length and kidney morphology. Frontiers in Cell and Developmental Biology, 14, Artikel 1805468. https://doi.org/10.3389/fcell.2026.1805468

Authier, F., Jan, A., Faress, I., Skoven, C. S., Esperon-Abril, I., Tharmakulasingam Balasubramaniam, S., Coquelin, K.-S., Nyengaard, J. R., Scavenius, C., Attianese, B., Sevillano-Quispe, O. G., Eskildsen, S. F., Thomsen, J. S., Hansen, B. & van Aalten, D. MF. (2026). Pathogenic O-GlcNAc dyshomeostasis is associated with cortical malformations and hyperactivity. eLife. Advance online publication. https://doi.org/10.7554/elife.107170.2

Neis, K., Civit Pitarch, L., Pedersen, K., Schachtner, M., Wengel, J., Wagner, R., Thiel, S., Kjems, J. & Valero Moreno, J. (2026). Lock, Protect, and Bind: In Vitro Selection of Locked Nucleic Acid-Modified Aptamers Using a Mutant T7 RNA Polymerase. Small Structures, 7(3), Artikel e202500677. https://doi.org/10.1002/sstr.202500677

Gázquez-Gutiérrez, A., Chin, P., Peris, G., Gordon, K., Marchante, P. G., Witteveldt, J., Tristán-Ramos, P., Rouvière, J. O., Knol, L. I., Ivens, A., López-Onieva, L., Estévez, A. M., Garland, W., Jensen, T. H., Heras, S. R. & Macias, S. (2026). Control of retrotransposon-driven activation of the interferon response by the double-stranded RNA binding protein DGCR8. Nucleic Acids Research, 54(5), Artikel gkag190. https://doi.org/10.1093/nar/gkag190

Møhlenberg, M., Jørgensen, S. E., Marije van der Sluis, R., Zillinger, T., Hinke, D. M., Hollensen, A. K., Hansen, A. L., Hausfater, P., Gorochov, G., Tubach, F., Ghosn, J., Laouenan, C., Storgaard, M., Holm, C. K., Su, H., Pérez de Diego, R., Pujol, A., Zhang, S.-Y., Zhang, Q. ... COVID Human Genetic Effort (2026). Defective RNA Polymerase III sensing of mitochondrial DNA in pulmonary epithelial cells impairs type I IFN immunity to SARS-CoV-2. Proceedings of the National Academy of Sciences of the United States of America, 123(12), Artikel e2522111123. https://doi.org/10.1073/pnas.2522111123

Mishra, A., Zubia-Aranburu, J., Zuzic, L., Saeed, K., Nielsen, J., Schio̷tt, B., Dong, M., Otzen, D. E. & Weidner, T. (2026). Structure of α-Synuclein Bound to Polystyrene Surfaces Probed by Experimental and Theoretical Sum Frequency Generation Spectroscopy. Langmuir : the ACS journal of surfaces and colloids, 42(11), 7653-7659. https://doi.org/10.1021/acs.langmuir.5c05658

Zhang, X., Hitt, P., Wanunu, M. & Kjems, J. (2026). Scalable Production of DNA-Probe-Functionalized Heteromeric MspA Nanopores for Biosensing. ACS Applied Materials and Interfaces, 18(10), 14531-14539. https://doi.org/10.1021/acsami.5c21011

Fischer, C. M., Edu, I. A., Šneideris, T., Baronaite, I., Toprakcioglu, Z., Deck, L.-T., Qian, D., Scrutton, R., Dreyer, L., Wen, J., Otzen, D. E., Wu, S., Perrett, S. & Knowles, T. P. J. (2026). Reversibility and β-sheet formation are decoupled in tau condensate aging. Proceedings of the National Academy of Sciences of the United States of America, 123(11), Artikel e2522993123. https://doi.org/10.1073/pnas.2522993123

Riedelbauch, S., Masser, S., Fasching, S., Lin, S. Y., Salgania, H. K., Aarup, M., Ebert, A., Jeske, M., Levine, M. T., Stelzl, U. & Andersen, P. (2026). Recurrent innovation of protein-protein interactions in the Drosophila piRNA pathway. EMBO Journal, 45(6), 1909-1932. Artikel 98. https://doi.org/10.1038/s44318-025-00439-8

Rodriguez, A., Formoso, E., Knudsen, B. R., Tesauro, C., Fuertes, M. & Alonso, C. (2026). Synthesis, Biological Evaluation, and Theoretical Study of Indenoquinolinylphosphine Oxide Derivatives as Topoisomerase 1 Inhibitors and Antiproliferative Agents. ChemMedChem, 21(5), Artikel e202500751. https://doi.org/10.1002/cmdc.202500751