Henriksen, T. V., Drue, S. O., Frydendahl, A., Demuth, C., Rasmussen, M. H., Reinert, T., Pedersen, J. S. & Andersen, C. L. (2022).
Error Characterization and Statistical Modeling Improves Circulating Tumor DNA Detection by Droplet Digital PCR.
Clinical Chemistry,
68(5), 657-667.
https://doi.org/10.1093/clinchem/hvab274
Mouritsen, K. N., Dalsgaard, N. P.
, Flensburg, S. B., Madsen, J. C.
& Selbach, C. (2022).
Fear of parasitism affects the functional role of ecosystem engineers.
Oikos,
2022(5), Artikel e08965.
https://doi.org/10.1111/oik.08965
Grotzinger, A. D., Mallard, T. T., Akingbuwa, W. A., Ip, H. F., Adams, M. J., Lewis, C. M., McIntosh, A. M.
, Grove, J., Dalsgaard, S., Lesch, K. P., Strom, N.
, Meier, S. M., Mattheisen, M., Børglum, A. D., Mors, O., Breen, G., iPSYCH, Tourette Syndrome and Obsessive Compulsive Disorder Working Group of the Psychiatric Genetics Consortium, Bipolar Disorder Working Group of the Psychiatric Genetics Consortium ... Nivard, M. G. (2022).
Genetic architecture of 11 major psychiatric disorders at biobehavioral, functional genomic and molecular genetic levels of analysis.
Nature Genetics,
54(5), 548-559.
https://doi.org/10.1038/s41588-022-01057-4
Feng, S., Bai, M.
, Rivas-González, I., Li, C., Liu, S., Tong, Y., Yang, H., Chen, G., Xie, D., Sears, K. E., Franco, L. M., Gaitan-Espitia, J. D., Nespolo, R. F., Johnson, W. E., Yang, H., Brandies, P. A., Hogg, C. J., Belov, K., Renfree, M. B. ... Zhang, G. (2022).
Incomplete lineage sorting and phenotypic evolution in marsupials.
Cell,
185(10), 1646-1660.e18.
https://doi.org/10.1016/j.cell.2022.03.034
Cortleven, A., Roeber, V. M.
, Frank, M., Bertels, J., Lortzing, V., Beemster, G. T. S. & Schmülling, T. (2022).
Photoperiod Stress in Arabidopsis thaliana Induces a Transcriptional Response Resembling That of Pathogen Infection.
Frontiers in Plant Science,
13, Artikel 838284.
https://doi.org/10.3389/fpls.2022.838284
Rasmussen, H. Ø., Wollenberg, D. T. W.
, Wang, H., Andersen, K. K., Oliveira, C. L. P., Jørgensen, C. I., Jørgensen, T. J. D.
, Otzen, D. E. & Pedersen, J. S. (2022).
The changing face of SDS denaturation: Complexes of Thermomyces lanuginosus lipase with SDS at pH 4.0, 6.0 and 8.0.
Journal of Colloid and Interface Science,
614, 214-232.
https://doi.org/10.1016/j.jcis.2021.12.188
Ommen, P., Hansen, L., Hansen, B. K., Vu-Quang, H., Kjems, J. & Meyer, R. L. (2022).
Aptamer-Targeted Drug Delivery for Staphylococcus aureus Biofilm.
Frontiers in Cellular and Infection Microbiology,
12, Artikel 814340.
https://doi.org/10.3389/fcimb.2022.814340
Trubetskoy, V., Pardiñas, A. F., Qi, T., Panagiotaropoulou, G., Awasthi, S., Bigdeli, T. B., Bryois, J., Chen, C.-Y., Dennison, C. A., Hall, L. S., Lam, M., Watanabe, K., Frei, O., Ge, T., Harwood, J. C., Koopmans, F., Magnusson, S., Richards, A. L., Sidorenko, J. ... Indonesia Schizophrenia Consortium (2022).
Mapping genomic loci implicates genes and synaptic biology in schizophrenia.
Nature,
604(7906), 502-508.
https://doi.org/10.1038/s41586-022-04434-5
Schubert, L., Hendriks, I. A., Hertz, E. P. T., Wu, W., Sellés-Baiget, S., Hoffmann, S., Viswalingam, K. S., Gallina, I., Pentakota, S., Benedict, B., Johansen, J., Apelt, K., Luijsterburg, M. S., Rasmussen, S., Lisby, M., Liu, Y.
, Nielsen, M. L., Mailand, N. & Duxin, J. P. (2022).
SCAI promotes error-free repair of DNA interstrand crosslinks via the Fanconi anemia pathway.
EMBO Reports,
23(4), Artikel e53639.
https://doi.org/10.15252/embr.202153639
Taber, A., Christensen, E., Lamy, P., Nordentoft, I., Prip, F., Lindskrog, S. V., Birkenkamp-Demtröder, K., Okholm, T. L. H., Knudsen, M., Pedersen, J. S., Steiniche, T., Agerbæk, M., Jensen, J. B. & Dyrskjøt, L. (2022).
Author Correction: Molecular correlates of cisplatin-based chemotherapy response in muscle invasive bladder cancer by integrated multi-omics analysis.
Nature Communications,
13(1), Artikel 1916.
https://doi.org/10.1038/s41467-022-29627-4
Dieudonné, T., Herrera, S. A.
, Laursen, M. J., Lejeune, M.
, Stock, C., Slimani, K., Jaxel, C.
, Lyons, J. A., Montigny, C., Pomorski, T. G.
, Nissen, P. & Lenoir, G. (2022).
Autoinhibition and regulation by phosphoinositides of ATP8B1, a human lipid flippase associated with intrahepatic cholestatic disorders.
eLife,
11, Artikel e75272.
https://doi.org/10.7554/eLife.75272
Meyer, F., Fritz, A., Deng, Z. L., Koslicki, D., Lesker, T. R., Gurevich, A., Robertson, G., Alser, M., Antipov, D., Beghini, F., Bertrand, D., Brito, J. J., Brown, C. T., Buchmann, J., Buluç, A., Chen, B., Chikhi, R., Clausen, P. T. L. C., Cristian, A. ... McHardy, A. C. (2022).
Critical Assessment of Metagenome Interpretation: the second round of challenges.
Nature Methods,
19(4), 429-440.
https://doi.org/10.1038/s41592-022-01431-4
Lucotte, E. A., Albiñana, C., Laurent, R., Bhérer, C.
, Bataillon, T., Toupance, B. & Genome of the Netherland Consortium (2022).
Detection of sexually antagonistic transmission distortions in trio datasets.
Evolution Letters,
6(2), 203-216.
https://doi.org/10.1002/evl3.271
Bataillon, T., Gauthier, P.
, Villesen, P., Santoni, S., Thompson, J. D.
& Ehlers, B. K. (2022).
From genotype to phenotype: Genetic redundancy and the maintenance of an adaptive polymorphism in the context of high gene flow.
Evolution Letters,
6(2), 189-202.
https://doi.org/10.1002/evl3.277
Bale, L. K., Schafer, M. J., Atkinson, E. J., Le Brasseur, N. K., Haak, A. J.
, Oxvig, C. & Conover, C. A. (2022).
Pregnancy-associated plasma protein-A (PAPP-A) is a key component of an interactive cellular mechanism promoting pulmonary fibrosis.
Journal of Cellular Physiology,
237(4), 2220-2229.
https://doi.org/10.1002/jcp.30687
Singh, T., Poterba, T., Curtis, D., Akil, H., Al Eissa, M., Barchas, J. D., Bass, N., Bigdeli, T. B., Breen, G., Bromet, E. J., Buckley, P. F., Bunney, W. E., Bybjerg-Grauholm, J., Byerley, W. F., Chapman, S. B., Chen, W. J., Churchhouse, C., Craddock, N., Cusick, C. M. ... Daly, M. J. (2022).
Rare coding variants in ten genes confer substantial risk for schizophrenia.
Nature,
604(7906), 509-516.
https://doi.org/10.1038/s41586-022-04556-w
Christensen, K. J.
, Dreier, J. W., Skotte, L., Feenstra, B.
, Grove, J., Børglum, A. D., Mitrovic, M., Cotsapas, C.
& Christensen, J. (2022).
Seasonal Variation and Risk of Febrile Seizures: A Danish Nationwide Cohort Study.
Neuroepidemiology,
56(2), 138-145.
https://doi.org/10.1159/000522065
Murphy, K. M., Poretsky, E.
, Liu, H., Micic, N., Nyhuis, A., Bohlmann, J., Schmelz, E. A., Zerbe, P., Huffaker, A. & Bjarnholt, N. (2022).
Shielding the oil reserves: The scutellum as a source of chemical defenses.
Plant Physiology,
188(4), 1944-1949.
https://doi.org/10.1093/plphys/kiac038
Langousis, G., Cavadini, S.
, Boegholm, N., Lorentzen, E., Kempf, G. & Matthias, P. (2022).
Structure of the ciliogenesis-associated CPLANE complex.
Science Advances,
8(15), Artikel eabn0832.
https://doi.org/10.1126/sciadv.abn0832
Pedersen, E. M., Agerbo, E., Plana-Ripoll, O., Grove, J., Dreier, J. W., Musliner, K. L., Bækvad-Hansen, M., Athanasiadis, G., Schork, A., Bybjerg-Grauholm, J., Hougaard, D. M., Werge, T., Nordentoft, M.
, Mors, O., Dalsgaard, S., Christensen, J., Børglum, A. D., Mortensen, P. B., McGrath, J. J. ... Vilhjálmsson, B. J. (2022).
Accounting for age of onset and family history improves power in genome-wide association studies.
American Journal of Human Genetics,
109(3), 417-432.
https://doi.org/10.1016/j.ajhg.2022.01.009
Gitto, R., Vittorio, S., Bucolo, F.
, Peña-Díaz, S., Siracusa, R., Cuzzocrea, S., Ventura, S., Di Paola, R. & De Luca, L. (2022).
Discovery of Neuroprotective Agents Based on a 5-(4-Pyridinyl)-1,2,4-triazole Scaffold.
ACS Chemical Neuroscience,
13(5), 581-586.
https://doi.org/10.1021/acschemneuro.1c00849
López de Las Hazas, M. C., Del Pozo-Acebo, L.
, Hansen, M. S., Gil-Zamorano, J., Mantilla-Escalante, D. C., Gómez-Coronado, D., Marín, F., Garcia-Ruiz, A.
, Rasmussen, J. T. & Dávalos, A. (2022).
Dietary bovine milk miRNAs transported in extracellular vesicles are partially stable during GI digestion, are bioavailable and reach target tissues but need a minimum dose to impact on gene expression.
European Journal of Nutrition,
61(2), 1043-1056.
https://doi.org/10.1007/s00394-021-02720-y
Frank, M., Cortleven, A., Pěnčík, A., Novak, O. & Schmülling, T. (2022).
The Photoperiod Stress Response in Arabidopsis thaliana Depends on Auxin Acting as an Antagonist to the Protectant Cytokinin.
International Journal of Molecular Sciences ,
23(6), Artikel 2936.
https://doi.org/10.3390/ijms23062936
Wang, T., Nielsen, K. L., Frisch, K., Lassen, J. K., Nielsen, C. B., Andersen, C. U., Villesen, P., Andreasen, M. F., Hasselstrøm, J. B. & Johannsen, M. (2022).
A Retrospective Metabolomics Analysis of Gamma-Hydroxybutyrate in Humans: New Potential Markers and Changes in Metabolism Related to GHB Consumption.
Frontiers in Pharmacology,
13, Artikel 816376.
https://doi.org/10.3389/fphar.2022.816376
Jankowski, V., Saritas, T.
, Kjolby, M., Hermann, J., Speer, T., Himmelsbach, A., Mahr, K., Heuschkel, M. A., Schunk, S. J.
, Thirup, S., Winther, S., Bottcher, M., Nyegard, M.
, Nykjaer, A., Kramann, R., Kaesler, N., Jankowski, J., Floege, J., Marx, N. & Goettsch, C. (2022).
Carbamylated sortilin associates with cardiovascular calcification in patients with chronic kidney disease.
Kidney International,
101(3), 574-584.
https://doi.org/10.1016/j.kint.2021.10.018
Møller, I. J. B., Utke, A. R., Rysgaard, U. K.
, Østergaard, L. J. & Jespersen, S. (2022).
Diagnostic performance, user acceptability, and safety of unsupervised SARS-CoV-2 rapid antigen-detecting tests performed at home.
International Journal of Infectious Diseases,
116, 358-364.
https://doi.org/10.1016/j.ijid.2022.01.019
Amorim Franchi, G., Jensen, M. B., Foldager, L., Larsen, M. & Herskin, M. S. (2022).
Effects of dietary and milking frequency changes and administration of cabergoline on clinical udder characteristics in dairy cows during dry-off.
Research in Veterinary Science,
143, 88-98.
https://doi.org/10.1016/j.rvsc.2021.12.019
Gomes-Duarte, A.
, Venø, M. T., de Wit, M., Senthilkumar, K., Broekhoven, M. H., van den Herik, J., Heeres, F. R., van Rossum, D., Rybiczka-Tesulov, M., Legnini, I., van Rijen, P. C., van Eijsden, P., Gosselaar, P. H., Rajewsky, N.
, Kjems, J., Vangoor, V. R. & Pasterkamp, R. J. (2022).
Expression of Circ_Satb1 Is Decreased in Mesial Temporal Lobe Epilepsy and Regulates Dendritic Spine Morphology.
Frontiers in Molecular Neuroscience,
15, Artikel 832133.
https://doi.org/10.3389/fnmol.2022.832133
Meldgaard, S. A., Köhler, J.
, Mortensen, H. L., Christiansen, M. P. V., Noé, F.
& Hammer, B. (2022).
Generating stable molecules using imitation and reinforcement learning.
Machine Learning: Science and Technology,
3(1), Artikel 015008.
https://doi.org/10.1088/2632-2153/ac3eb4
Reimer, L., Haikal, C.
, Gram, H., Theologidis, V., Kovacs, G., Ruesink, H., Baun, A., Nielsen, J., Otzen, D. E., Li, J.-Y.
& Jensen, P. H. (2022).
Low dose DMSO treatment induces oligomerization and accelerates aggregation of α-synuclein.
Scientific Reports,
12, Artikel 3737.
https://doi.org/10.1038/s41598-022-07706-2
Teodori, L., Omer, M., Märcher, A., Skaanning, M. K., Andersen, V. L., Nielsen, J. S., Oldenburg, E., Lin, Y., Gothelf, K. V. & Kjems, J. (2022).
Site-specific nanobody-oligonucleotide conjugation for super-resolution imaging.
Journal of Biological Methods,
9(1), Artikel e159.
https://doi.org/10.14440/jbm.2022.381
Nielsen, J., Brandt, J.
, Boesen, T., Hummelshøj, T., Slaaby, R., Schluckebier, G.
& Nissen, P. (2022).
Structural investigations of full-length insulin receptor dynamics and signalling.
Journal of Molecular Biology,
434(5), Artikel 167458.
https://doi.org/10.1016/j.jmb.2022.167458
Gu, T., Just, J., Stenz, K. T., Yan, Y., Sieljacks, P., Wang, J., Groennebaek, T. S., Jakobsgaard, J. E., Rindom, E., Herskind, J., Gravholt, A.
, Lassen, T. R., Jørgensen, M., Bæk, R.
, Gutiérrez-Jiménez, E., Iversen, N. K., Rasmussen, P. M., Nyengaard, J. R., Jørgensen, M. M.
... Drasbek, K. R. (2022).
The Role of Plasma Extracellular Vesicles in Remote Ischemic Conditioning and Exercise-Induced Ischemic Tolerance.
International Journal of Molecular Sciences ,
23(6), Artikel 3334.
https://doi.org/10.3390/ijms23063334
Christensen, N. R., Pedersen, C. P., Sereikaite, V.
, Pedersen, J. N., Vistrup-Parry, M., Sørensen, A. T.
, Otzen, D., Teilum, K., Madsen, K. L. & Strømgaard, K. (2022).
Bidirectional protein-protein interactions control liquid-liquid phase separation of PSD-95 and its interaction partners.
iScience,
25(2), Artikel 103808.
https://doi.org/10.1016/j.isci.2022.103808
Farzadfard, A., Pedersen, J. N., Meisl, G.
, Somavarapu, A. K., Alam, P., Goksøyr, L., Nielsen, M. A., Sander, A. F., Knowles, T. P. J.
, Pedersen, J. S. & Otzen, D. E. (2022).
The C-terminal tail of α-synuclein protects against aggregate replication but is critical for oligomerization.
Communications Biology,
5(1), 123. Artikel 123.
https://doi.org/10.1038/s42003-022-03059-8
Skotte, L., Fadista, J., Bybjerg-Grauholm, J., Appadurai, V., Hildebrand, M. S., Hansen, T. F., Banasik, K.
, Grove, J., Albiñana, C., Geller, F., Bjurström, C. F.
, Vilhjálmsson, B. J., Coleman, M., Damiano, J. A., Burgess, R., Scheffer, I. E., Pedersen, O. B. V.
, Erikstrup, C., Westergaard, D. ... Feenstra, B. (2022).
Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes.
Brain : a journal of neurology,
145(2), 555–568.
https://doi.org/10.1093/brain/awab260
Fuertes, M., Selas, A., Trejo, A.
, Knudsen, B. R., Palacios, F. & Alonso, C. (2022).
Synthesis of hybrid phosphorated indenoquinolines and biological evaluation as topoisomerase I inhibitors and antiproliferative agents.
Bioorganic & Medicinal Chemistry Letters,
57, Artikel 128517.
https://doi.org/10.1016/j.bmcl.2021.128517
Dinesen, A., Winther, A., Wall, A.
, Märcher, A., Palmfeldt, J., Chudasama, V., Wengel, J.
, Gothelf, K. V., Baker, J. R.
& Howard, K. A. (2022).
Albumin Biomolecular Drug Designs Stabilized through Improved Thiol Conjugation and a Modular Locked Nucleic Acid Functionalized Assembly.
Bioconjugate Chemistry,
33(2), 333-342.
https://doi.org/10.1021/acs.bioconjchem.1c00561
Gómez-Cuadrado, L., Bullock, E., Mabruk, Z., Zhao, H., Souleimanova, M.
, Noer, P. R., Turnbull, A. K.
, Oxvig, C., Bertos, N., Byron, A., Dixon, J. M., Park, M., Haider, S., Natrajan, R., Sims, A. H. & Brunton, V. G. (2022).
Characterisation of the Stromal Microenvironment in Lobular Breast Cancer.
Cancers,
14(4), Artikel 904.
https://doi.org/10.3390/cancers14040904