Langousis, G., Cavadini, S.
, Boegholm, N., Lorentzen, E., Kempf, G. & Matthias, P. (2022).
Structure of the ciliogenesis-associated CPLANE complex.
Science Advances,
8(15), Artikel eabn0832.
https://doi.org/10.1126/sciadv.abn0832
Pedersen, E. M., Agerbo, E., Plana-Ripoll, O., Grove, J., Dreier, J. W., Musliner, K. L., Bækvad-Hansen, M., Athanasiadis, G., Schork, A., Bybjerg-Grauholm, J., Hougaard, D. M., Werge, T., Nordentoft, M.
, Mors, O., Dalsgaard, S., Christensen, J., Børglum, A. D., Mortensen, P. B., McGrath, J. J. ... Vilhjálmsson, B. J. (2022).
Accounting for age of onset and family history improves power in genome-wide association studies.
American Journal of Human Genetics,
109(3), 417-432.
https://doi.org/10.1016/j.ajhg.2022.01.009
López de Las Hazas, M. C., Del Pozo-Acebo, L.
, Hansen, M. S., Gil-Zamorano, J., Mantilla-Escalante, D. C., Gómez-Coronado, D., Marín, F., Garcia-Ruiz, A.
, Rasmussen, J. T. & Dávalos, A. (2022).
Dietary bovine milk miRNAs transported in extracellular vesicles are partially stable during GI digestion, are bioavailable and reach target tissues but need a minimum dose to impact on gene expression.
European Journal of Nutrition,
61(2), 1043-1056.
https://doi.org/10.1007/s00394-021-02720-y
Frank, M., Cortleven, A., Pěnčík, A., Novak, O. & Schmülling, T. (2022).
The Photoperiod Stress Response in Arabidopsis thaliana Depends on Auxin Acting as an Antagonist to the Protectant Cytokinin.
International Journal of Molecular Sciences ,
23(6), Artikel 2936.
https://doi.org/10.3390/ijms23062936
Wang, T., Nielsen, K. L., Frisch, K., Lassen, J. K., Nielsen, C. B., Andersen, C. U., Villesen, P., Andreasen, M. F., Hasselstrøm, J. B. & Johannsen, M. (2022).
A Retrospective Metabolomics Analysis of Gamma-Hydroxybutyrate in Humans: New Potential Markers and Changes in Metabolism Related to GHB Consumption.
Frontiers in Pharmacology,
13, Artikel 816376.
https://doi.org/10.3389/fphar.2022.816376
Jankowski, V., Saritas, T.
, Kjolby, M., Hermann, J., Speer, T., Himmelsbach, A., Mahr, K., Heuschkel, M. A., Schunk, S. J.
, Thirup, S., Winther, S., Bottcher, M., Nyegard, M.
, Nykjaer, A., Kramann, R., Kaesler, N., Jankowski, J., Floege, J., Marx, N. & Goettsch, C. (2022).
Carbamylated sortilin associates with cardiovascular calcification in patients with chronic kidney disease.
Kidney International,
101(3), 574-584.
https://doi.org/10.1016/j.kint.2021.10.018
Amorim Franchi, G., Jensen, M. B., Foldager, L., Larsen, M. & Herskin, M. S. (2022).
Effects of dietary and milking frequency changes and administration of cabergoline on clinical udder characteristics in dairy cows during dry-off.
Research in Veterinary Science,
143, 88-98.
https://doi.org/10.1016/j.rvsc.2021.12.019
Gomes-Duarte, A.
, Venø, M. T., de Wit, M., Senthilkumar, K., Broekhoven, M. H., van den Herik, J., Heeres, F. R., van Rossum, D., Rybiczka-Tesulov, M., Legnini, I., van Rijen, P. C., van Eijsden, P., Gosselaar, P. H., Rajewsky, N.
, Kjems, J., Vangoor, V. R. & Pasterkamp, R. J. (2022).
Expression of Circ_Satb1 Is Decreased in Mesial Temporal Lobe Epilepsy and Regulates Dendritic Spine Morphology.
Frontiers in Molecular Neuroscience,
15, Artikel 832133.
https://doi.org/10.3389/fnmol.2022.832133
Reimer, L., Haikal, C.
, Gram, H., Theologidis, V., Kovacs, G., Ruesink, H., Baun, A., Nielsen, J., Otzen, D. E., Li, J.-Y.
& Jensen, P. H. (2022).
Low dose DMSO treatment induces oligomerization and accelerates aggregation of α-synuclein.
Scientific Reports,
12, Artikel 3737.
https://doi.org/10.1038/s41598-022-07706-2
Ung, K. L., Alsarraf, H., Kremer, L. & Blaise, M. (2022).
MmpL3, the trehalose monomycolate transporter, is stable in solution in several detergents and can be reconstituted into peptidiscs.
Protein Expression and Purification,
191, Artikel 106014.
https://doi.org/10.1016/j.pep.2021.106014
Teodori, L., Omer, M., Märcher, A., Skaanning, M. K., Andersen, V. L., Nielsen, J. S., Oldenburg, E., Lin, Y., Gothelf, K. V. & Kjems, J. (2022).
Site-specific nanobody-oligonucleotide conjugation for super-resolution imaging.
Journal of Biological Methods,
9(1), Artikel e159.
https://doi.org/10.14440/jbm.2022.381
Nielsen, J., Brandt, J.
, Boesen, T., Hummelshøj, T., Slaaby, R., Schluckebier, G.
& Nissen, P. (2022).
Structural investigations of full-length insulin receptor dynamics and signalling.
Journal of Molecular Biology,
434(5), Artikel 167458.
https://doi.org/10.1016/j.jmb.2022.167458
Gu, T., Just, J., Stenz, K. T., Yan, Y., Sieljacks, P., Wang, J., Groennebaek, T. S., Jakobsgaard, J. E., Rindom, E., Herskind, J., Gravholt, A.
, Lassen, T. R., Jørgensen, M., Bæk, R.
, Gutiérrez-Jiménez, E., Iversen, N. K., Rasmussen, P. M., Nyengaard, J. R., Jørgensen, M. M.
... Drasbek, K. R. (2022).
The Role of Plasma Extracellular Vesicles in Remote Ischemic Conditioning and Exercise-Induced Ischemic Tolerance.
International Journal of Molecular Sciences ,
23(6), Artikel 3334.
https://doi.org/10.3390/ijms23063334
Fuertes, M., Selas, A., Trejo, A.
, Knudsen, B. R., Palacios, F. & Alonso, C. (2022).
Synthesis of hybrid phosphorated indenoquinolines and biological evaluation as topoisomerase I inhibitors and antiproliferative agents.
Bioorganic and Medicinal Chemistry Letters,
57, Artikel 128517.
https://doi.org/10.1016/j.bmcl.2021.128517
Christensen, N. R., Pedersen, C. P., Sereikaite, V.
, Pedersen, J. N., Vistrup-Parry, M., Sørensen, A. T.
, Otzen, D., Teilum, K., Madsen, K. L. & Strømgaard, K. (2022).
Bidirectional protein-protein interactions control liquid-liquid phase separation of PSD-95 and its interaction partners.
iScience,
25(2), Artikel 103808.
https://doi.org/10.1016/j.isci.2022.103808
Marquez-Legorreta, E., Constantin, L., Piber, M., Favre-Bulle, I. A., Taylor, M. A., Blevins, A. S., Giacomotto, J., Bassett, D. S.
, Vanwalleghem, G. C. & Scott, E. K. (2022).
Brain-wide visual habituation networks in wild type and fmr1 zebrafish.
Nature Communications,
13(1), Artikel 895.
https://doi.org/10.1038/s41467-022-28299-4
Gómez-Cuadrado, L., Bullock, E., Mabruk, Z., Zhao, H., Souleimanova, M., Noer, P. R., Turnbull, A. K.
, Oxvig, C., Bertos, N., Byron, A., Dixon, J. M., Park, M., Haider, S., Natrajan, R., Sims, A. H. & Brunton, V. G. (2022).
Characterisation of the Stromal Microenvironment in Lobular Breast Cancer.
Cancers,
14(4), Artikel 904.
https://doi.org/10.3390/cancers14040904
Madzharova, F., Bregnhøj, M., Chatterley, A. S., Løvschall, K. B., Drace, T., Andersen Dreyer, L. S., Boesen, T. & Weidner, T. (2022).
Electrostatics Trigger Interfacial Self-Assembly of Bacterial Ice Nucleators.
Biomacromolecules,
23(2), 505-512.
https://doi.org/10.1021/acs.biomac.1c01217
Rafiq, M., Ernst, H. A., Aduri, N. G., Prabhala, B. K., Tufail, S., Rahman, M., Bloch, M. B., Mirza, N., Taylor, N. M. I.
, Boesen, T., Gajhede, M. & Mirza, O. (2022).
Expression, purification and characterization of human proton-coupled oligopeptide transporter 1 hPEPT1.
Protein Expression and Purification,
190, Artikel 105990.
https://doi.org/10.1016/j.pep.2021.105990
Skotte, L., Fadista, J., Bybjerg-Grauholm, J., Appadurai, V., Hildebrand, M. S., Hansen, T. F., Banasik, K.
, Grove, J., Albiñana, C., Geller, F., Bjurström, C. F.
, Vilhjálmsson, B. J., Coleman, M., Damiano, J. A., Burgess, R., Scheffer, I. E., Pedersen, O. B. V.
, Erikstrup, C., Westergaard, D. ... Feenstra, B. (2022).
Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes.
Brain : a journal of neurology,
145(2), 555–568.
https://doi.org/10.1093/brain/awab260
Gupta, K. J., Kaladhar, V. C., Fitzpatrick, T. B., Fernie, A. R.
, Møller, I. M. & Loake, G. J. (2022).
Nitric oxide regulation of plant metabolism.
Molecular Plant,
15(2), 228-242.
https://doi.org/10.1016/j.molp.2021.12.012
Cavassim, M. I. A., Baker, Z., Hoge, C.
, Schierup, M. H., Schumer, M. & Przeworski, M. (2022).
PRDM9 losses in vertebrates are coupled to those of paralogs ZCWPW1 and ZCWPW2.
Proceedings of the National Academy of Sciences,
119(9), Artikel e2114401119.
https://doi.org/10.1073/pnas.2114401119
Gockert, M., Schmid, M., Jakobsen, L., Jens, M., Andersen, J. S.
& Jensen, T. H. (2022).
Rapid factor depletion highlights intricacies of nucleoplasmic RNA degradation.
Nucleic Acids Research,
50(3), 1583-1600.
https://doi.org/10.1093/nar/gkac001
Jakobsen, A. K., Yuusufi, S., Madsen, L. B., Meldgaard, P., Knudsen, B. R. & Stougaard, M. (2022).
TDP1 and TOP1 as targets in anticancer treatment of NSCLC: Activity and protein level in normal and tumor tissue from 150 NSCLC patients correlated to clinical data.
Lung Cancer,
164, 23-32.
https://doi.org/10.1016/j.lungcan.2021.12.010,
https://doi.org/10.1016/j.lungcan.2021.12.010
Farzadfard, A., Pedersen, J. N., Meisl, G.
, Somavarapu, A. K., Alam, P., Goksøyr, L., Nielsen, M. A., Sander, A. F., Knowles, T. P. J.
, Pedersen, J. S. & Otzen, D. E. (2022).
The C-terminal tail of α-synuclein protects against aggregate replication but is critical for oligomerization.
Communications Biology,
5(1), Artikel 123.
https://doi.org/10.1038/s42003-022-03059-8
Chaptal, V., Zampieri, V., Wiseman, B., Orelle, C., Martin, J., Nguyen, K.-A.
, Gobet, A., Di Cesare, M., Magnard, S., Javed, W., Eid, J., Kilburg, A., Peuchmaur, M., Marcoux, J., Monticelli, L., Hogbom, M., Schoehn, G., Jault, J.-M., Boumendjel, A. & Falson, P. (2022).
Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter.
Science Advances,
8(4), eabg9215.
https://doi.org/10.1126/sciadv.abg9215
Nørgård, M., Steffensen, L. B., Hansen, D. R.
, Füchtbauer, E. M., Engelund, M. B., Dimke, H., Andersen, D. C. & Svenningsen, P. (2022).
A new transgene mouse model using an extravesicular EGFP tag enables affinity isolation of cell-specific extracellular vesicles.
Scientific Reports,
12, Artikel 496.
https://doi.org/10.1038/s41598-021-04512-0
Mohammad-Beigi, H., Zanganeh, M.
, Scavenius, C., Eskandari, H., Farzadfard, A., Shojaosadati, S. A.
, Enghild, J. J., Otzen, D. E., Buell, A. K.
& Sutherland, D. S. (2022).
A Protein Corona Modulates Interactions of α-Synuclein with Nanoparticles and Alters the Rates of the Microscopic Steps of Amyloid Formation.
ACS Nano,
16(1), 1102-1118.
https://doi.org/10.1021/acsnano.1c08825
Nagaraj, M., Najarzadeh, Z., Pansieri, J., Biverstål, H., Musteikyte, G., Smirnovas, V., Matthews, S., Emanuelsson, C., Johansson, J., Buxbaum, J. N., Morozova-Roche, L.
& Otzen, D. E. (2022).
Chaperones mainly suppress primary nucleation during formation of functional amyloid required for bacterial biofilm formation.
Chemical Science,
13(2), 536-553.
https://doi.org/10.1039/d1sc05790a
Schendel, D., Munk Laursen, T., Albiñana, C., Vilhjalmsson, B., Ladd-Acosta, C., Fallin, M. D., Benke, K., Lee, B.
, Grove, J., Kalkbrenner, A.
, Ejlskov, L., Hougaard, D., Bybjerg-Grauholm, J., Baekvad-Hansen, M.
, Børglum, A. D., Werge, T., Nordentoft, M.
, Mortensen, P. B. & Agerbo, E. (2022).
Evaluating the interrelations between the autism polygenic score and psychiatric family history in risk for autism.
Autism Research,
15(1), 171-182.
https://doi.org/10.1002/aur.2629
Dahl, M., Husby, S., Eskelund, C. W.
, Besenbacher, S., Fjelstrup, S., Côme, C., Ek, S., Kolstad, A., Räty, R., Jerkeman, M., Geisler, C. H.
, Kjems, J., Kristensen, L. S. & Grønbæk, K. (2022).
Expression patterns and prognostic potential of circular RNAs in mantle cell lymphoma: a study of younger patients from the MCL2 and MCL3 clinical trials.
Leukemia,
36(1), 177-188.
https://doi.org/10.1038/s41375-021-01311-4
Sønderby, T. V., Rasmussen, H. Ø., Frank, S. A., Skov Pedersen, J. & Otzen, D. E. (2022).
Folding steps in the fibrillation of functional amyloid: denaturant sensitivity reveals common features in nucleation and elongation.
Journal of Molecular Biology,
434(2), Artikel 167337.
https://doi.org/10.1016/j.jmb.2021.167337
Petersen, G., Shyama Prasad Rao, R., Anderson, B.
, Zervas, A., Seberg, O., Rasmusson, A. G.
& Max Møller, I. (2022).
Genes from oxidative phosphorylation complexes II-V and two dual-function subunits of complex I are transcribed in Viscum album despite absence of the entire mitochondrial holo-complex I.
Mitochondrion,
62, 1-12.
https://doi.org/10.1016/j.mito.2021.10.006
Najarzadeh, Z., Mohammad-Beigi, H., Pedersen, J. N., Christiansen, G.
, Pedersen, J. S., Nielsen, J. & Otzen, D. E. (2022).
Interaction of membrane vesicles with the Pseudomonas functional amyloid protein FapC facilitates amyloid formation. BBA advances,
2, Artikel 100055.
https://doi.org/10.1016/j.bbadva.2022.100055
Moeskjær, S., Skovbjerg, C. K., Tausen, M., Wind, R., Roulund, N.
, Janss, L. & Andersen, S. U. (2022).
Major effect loci for plant size before onset of nitrogen fixation allow accurate prediction of yield in white clover.
Theoretical and Applied Genetics,
135(1), 125-143.
https://doi.org/10.1007/s00122-021-03955-3
Meron, E., Thaysen, M., Angeli, S., Antebi, A., Barzilai, N., Baur, J. A., Bekker-Jensen, S., Birkisdottir, M., Bischof, E., Bruening, J., Brunet, A., Buchwalter, A., Cabreiro, F., Cai, S., Chen, B. H., Ermolaeva, M., Ewald, C. Y., Ferrucci, L., Florian, M. C. ... Scheibye-Knudsen, M. (2022).
Meeting Report: Aging Research and Drug Discovery.
Aging,
14(2), 532-543.
https://doi.org/10.18632/aging.203859
Blokland, G. A. M.
, Grove, J., Chen, C. Y., Cotsapas, C., Tobet, S., Handa, R., Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium & iPSYCH (2022).
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders.
Biological Psychiatry,
91(1), 102-117.
https://doi.org/10.1016/j.biopsych.2021.02.972
Winkler, M. B. L., Nel, L., Frain, K. M., Dedic, E., Olesen, E. & Pedersen, B. P. (2022).
Sterol uptake by the NPC system in eukaryotes: a Saccharomyces cerevisiae perspective.
FEBS Letters,
596(2), 160-179.
https://doi.org/10.1002/1873-3468.14253