Aarhus University Seal / Aarhus Universitets segl

News

Nuclear mRNAs carry an ‘A tail’ at their end. Under normal conditions (left panel) the protein Nab2 binds to the A tail and this protects the RNA against decay, which allows RNA to be exported to the cytoplasm with the help of Mex67. Under export block conditions (right panel), Nab2 binds to the A-tailed RNAs accumulating in the nucleus and therefore gets in short supply for protecting newly made RNA, which instead gets degraded already in the cell nucleus by enzymes attacking it from the A tail end. Figure: Manfred Schmid.

30.08.2018 | Forskning

New method uncovers the importance of keeping a good nuclear RNA hygiene

How cells translate their genetic information into functional RNA and protein is a central question in biology. Researchers from the Department of Molecular Biology and Genetics at Aarhus University have invented a new technology to study regulatory principles of gene expression. Applying this methodology to bakers yeast they found that RNAs that…

28.05.2018 | Forskning, Udgivelse

New nuclear RNA retention activity discovered

Gene expression involves mRNA transport from its place of synthesis to the cytoplasm where protein translation occurs. However, many non-coding RNA species do not follow this flow and new data now demonstrate how cells prevent the unwanted export of RNA and instead ensure nuclear degradation.

16.04.2018 | Forskning

Ewa Molska, PhD

Ewa defended her PhD on April, 10th. Congratulations and Good Luck with your future!

04.01.2018 | Udgivelse, Forskning

Researchers reveal dual role for human RNA decay factor

Researchers at Aarhus University have characterized the human RNA decay factor ZC3H18 and discovered its unanticipated role in the production of protein-coding RNA. The new study, published this week in Cell Reports, therefore reveals a double-faced activity of ZC3H18 in nuclear RNA fate decisions.

Ross
Guifen
Jerome
Dennis
Toshi

25.04.2017 | Medarbejdernyhed

New members and one farewell

We are welcoming PhD student Dennis Johnsen and PostDocs Ross Cordiner, Jerome Rouviere, Guifen Wui and Katsutoshi Imamura who joined recently to the lab. But we also had to say goodbye to Kinga who left for a PostDoc in the UK.

Viser resultater 6 til 10 ud af 30

Forrige 1 2 3 4 5 6 Næste