Institut for Molekylærbiologi og Genetik

Aarhus Universitets segl

Neurobiologi

DANDRITE's logo

The Section for Neurobiology is part of the Danish Research Institute of Translational Neuroscience – DANDRITE 

- the Danish node of the Nordic EMBL Partnership for Molecular Medicine, which performs basic and translational research in brain and the nervous system.  

Groups at DANDRITE encompass ambitious research programs that include:

  • Molecular and cellular mechanisms of memory
  • Effort-based decision making
  • Neuronal development and stem cells
  • Motor control
  • Brain processing of vision
  • Neurological and neurodegenerative diseases
  • Psychiatric disorders
  • Neurotrophic receptors, sorting
  • Structural biology of membrane transporters and receptors

Read more about the research at DANDRITE.

Below you see the list of researchers at DANDRITE affiliated with the Department of Molecular Biology and Genetics.

Professor

Lektorer

Tenure Track Adjunkt

Peer-reviewed publikationer

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Sørensen, C. S. & Kjaergaard, M. (2020). Measuring Effective Concentrations Enforced by Intrinsically Disordered Linkers. I B. B. Kragelund & K. Skriver (red.), Methods in Molecular Biology: Methods and protocols (s. 505-518). Humana Press. https://doi.org/10.1007/978-1-0716-0524-0_25
Sonntag, Y., Musgaard, M., Olesen, C., Schiøtt, B., Møller, J. V., Nissen, P. & Thøgersen, L. (2011). Mutual adaptation of a membrane protein and its lipid bilayer during conformational changes. Nature Communications, 2, 304. https://doi.org/10.1038/ncomms1307
Skjørringe, T., Pedersen, P. A., Thorborg, S. S., Nissen, P., Gourdon, P. & Møller, L. B. (2017). Characterization of ATP7A missense mutants suggests a correlation between intracellular trafficking and severity of Menkes disease. Scientific Reports, 7(1), Artikel 757. https://doi.org/10.1038/s41598-017-00618-6
Sitsel, O., Grønberg, C., Autzen, H., Wang, K., Meloni, G., Nissen, P. & Gourdon, P. (2015). Structure and function of Cu(I)- and Zn(II)-ATPases. Biochemistry, 54(37), 5673-5683. https://doi.org/10.1021/acs.biochem.5b00512
Sitsel, A., De Raeymaecker, J., Drachmann, N. D., Derua, R., Smaardijk, S., Andersen, J. L., Vandecaetsbeek, I., Chen, J., De Maeyer, M., Waelkens, E., Olesen, C., Vangheluwe, P. & Nissen, P. (2019). Structures of the heart specific SERCA2a Ca 2+ -ATPase. EMBO Journal, 38(5), Artikel e100020. https://doi.org/10.15252/embj.2018100020
Shammas, S. L., Garcia, G. A., Kumar, S., Kjaergaard, M., Horrocks, M. H., Shivji, N., Mandelkow, E., Knowles, T. P. J., Mandelkow, E. & Klenerman, D. (2015). A mechanistic model of tau amyloid aggregation based on direct observation of oligomers. Nature Communications, 6, 7025. https://doi.org/10.1038/ncomms8025
Shahsavar, A., Stohler, P., Bourenkov, G., Zimmermann, I., Siegrist, M., Guba, W., Pinard, E., Sinning, S., Seeger, M. A., Schneider, T. R., Dawson, R. J. P. & Nissen, P. (2021). Structural insights into the inhibition of glycine reuptake. Nature, 591(7851), 677-681. https://doi.org/10.1038/s41586-021-03274-z
Sengupta, J., Nilsson, J., Gursky, R., Spahn, C. M. T., Nissen, P. & Frank, J. (2004). Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-electron microscopy. Nat. Struct. Biol. ,11, 957-962.
Sehgal, P., Szalai, P., Olesen, C., Praetorius, H. A., Nissen, P., Christensen, S. B., Engedal, N. & Møller, J. V. (2017). Inhibition of the sarco/endoplasmic reticulum (ER) Ca2+-ATPase by thapsigargin analogs induces cell death via ER Ca2+ depletion and the unfolded protein response. Journal of Biological Chemistry, 292(48), 19656-19673. https://doi.org/10.1074/jbc.M117.796920
Schmieder, S. S., Cordara, G., Kersten, F., Steiner, K., Samim, C. H., Plaza, D. F., Ali-Ahmad, A., Boeggild, A., Karlsen, J. L., Sokolowska, B. O., Boesen, T., Krengel, U. & Künzler, M. (2026). Structure and function of a fungal AB toxin-like chimerolectin involved in anti-nematode defense. EMBO Journal. Advance online publication. https://doi.org/10.1038/s44318-026-00812-1
Schack, V. R., Morth, J. P., Toustrup-Jensen, M. S., Anthonisen, A. N., Nissen, P., Andersen, J. P. & Vilsen, B. (2008). Identification and function of a cytoplasmic K+ site of the Na+,K+ATPase. Journal of Biological Chemistry, 283(41), 27982-90. https://doi.org/10.1074/jbc.M803506200
Saleh, N., Wang, Y., Nissen, P. & Lindorff-Larsen, K. (2019). Allosteric modulation of the sarcoplasmic reticulum Ca2+ ATPase by thapsigargin via decoupling of functional motions. Physical Chemistry Chemical Physics, 21(39), 21991-21995. https://doi.org/10.1039/c9cp04736k

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Revideret 13.11.2025
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Helene Eriksen