Institut for Molekylærbiologi og Genetik

Aarhus Universitets segl

Neurobiologi

DANDRITE's logo

The Section for Neurobiology is part of the Danish Research Institute of Translational Neuroscience – DANDRITE 

- the Danish node of the Nordic EMBL Partnership for Molecular Medicine, which performs basic and translational research in brain and the nervous system.  

Groups at DANDRITE encompass ambitious research programs that include:

  • Molecular and cellular mechanisms of memory
  • Effort-based decision making
  • Neuronal development and stem cells
  • Motor control
  • Brain processing of vision
  • Neurological and neurodegenerative diseases
  • Psychiatric disorders
  • Neurotrophic receptors, sorting
  • Structural biology of membrane transporters and receptors

Read more about the research at DANDRITE.

Below you see the list of researchers at DANDRITE affiliated with the Department of Molecular Biology and Genetics.

Professor

Lektorer

Tenure Track Adjunkt

Peer-reviewed publikationer

Sortér efter: Dato | Forfatter | Titel

Thorsen, T. S., Kulkarni, Y., Sykes, D. A., Bøggild, A., Drace, T., Hompluem, P., Iliopoulos-Tsoutsouvas, C., Nikas, S. P., Daver, H., Makriyannis, A., Nissen, P., Gajhede, M., Veprintsev, D. B., Boesen, T., Kastrup, J. S. & Gloriam, D. E. (2025). Structural basis of THC analog activity at the Cannabinoid 1 receptor. Nature Communications, 16(1), Artikel 486. https://doi.org/10.1038/s41467-024-55808-4
Timcenko, M., Dieudonné, T., Montigny, C., Boesen, T., Lyons, J. A., Lenoir, G. & Nissen, P. (2021). Structural Basis of Substrate-Independent Phosphorylation in a P4-ATPase Lipid Flippase. Journal of Molecular Biology, 433(16), Artikel 167062. https://doi.org/10.1016/j.jmb.2021.167062
Tidow, H., Mattle, D. & Nissen, P. (2011). Structural and biophysical characterisation of agrin laminin G3 domain constructs. Protein Engineering, Design and Selection, 24(1-2), 219-224. https://doi.org/10.1093/protein/gzq082
Dedic, E., Seweryn, P., Jonstrup, A. T., Flygaard, R. K., Fedosova, N. U., Hoffmann, S. V., Boesen, T. & Brodersen, D. E. (2014). Structural analysis of the yeast exosome Rrp6p-Rrp47p complex by small-angle x-ray scattering. Biochemical and Biophysical Research Communications, 450(1), 634-640. https://doi.org/10.1016/j.bbrc.2014.06.032
Montigny, C., Decottignies, P., le Maréchal, P., Capy, P., Bublitz, M., Olesen, C., Møller, J. V., le Maire, M. & Nissen, P. (2014). S-Palmitoylation and S-Oleoylation of Rabbit and Pig Sarcolipin. Journal of Biological Chemistry, 289, 33850-33861. https://doi.org/10.1074/jbc.M114.590307
Azizan, E. A. B., Poulsen, H., Tuluc, P., Zhou, J., Clausen, M., Lieb, A., Maniero, C., Garg, S., Bochukova, E. G., Zhao, W., Shaikh, L. H., Brighton, C. A., Teo, A. E. D., Davenport, A. P., Dekkers, T., Tops, B., Küsters, B., Ceral, J., Yeo, G. S. H. ... Brown, M. J. (2013). Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension. Nature Genetics, 45(9), 1055-1060. https://doi.org/10.1038/ng.2716
Kjærgaard, M., Gårdsvoll, H., Hirschberg, D., Nielbo, S., Mayasundari, A., Peterson, C. B., Jansson, A., Jørgensen, T. J. D., Poulsen, F. M. & Ploug, M. (2007). Solution structure of recombinant somatomedin B domain from vitronectin produced in Pichia pastoris. Protein Science, 16(9), 1934-45. https://doi.org/10.1110/ps.072949607
Bay, Y., Venskutonytė, R., Frantsen, S. M., Thorsen, T. S., Musgaard, M., Frydenvang, K., Francotte, P., Pirotte, B., Biggin, P. C., Kristensen, A. S., Boesen, T., Pickering, D. S., Gajhede, M. & Kastrup, J. S. (2024). Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure. FEBS journal, 291(7), 1506-1529. https://doi.org/10.1111/febs.17046
Sun, C. (2024). Single-Molecule-Resolution Approaches in Synaptic Biology. Journal of Physical Chemistry B, 128(13), 3061-3068. https://doi.org/10.1021/acs.jpcb.3c08026
Horrocks, M. H., Rajah, L., Jönsson, P., Kjærgaard, M., Vendruscolo, M., Knowles, T. P. J. & Klenerman, D. (2013). Single-molecule measurements of transient biomolecular complexes through microfluidic dilution. Analytical Chemistry, 85(14), 6855-9. https://doi.org/10.1021/ac4010875
Horrocks, M. H., Lee, S. F., Gandhi, S., Magdalinou, N. K., Chen, S. W., Devine, M. J., Tosatto, L., Kjaergaard, M., Beckwith, J. S., Zetterberg, H., Iljina, M., Cremades, N., Dobson, C. M., Wood, N. W. & Klenerman, D. (2016). Single-molecule imaging of individual amyloid protein aggregates in human biofluids. ACS Chemical Neuroscience, 7(3), 399–406. https://doi.org/10.1021/acschemneuro.5b00324
De Pol, F., Baranowski, M., Neumann, C., Trampari, S., Nissen, P. & Pérez, J. (2024). Simulation and modelling of the detergent corona around the membrane protein MhsT based on SAXS data. Journal of Applied Crystallography, 57, 1415-1425. https://doi.org/10.1107/S1600576724006721

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Revideret 13.11.2025
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Helene Eriksen