Publikationer

Publikationer fra instituttet

Tidsskriftsforsider lavet af forskere fra MBG

Peer-review'ede publikationer ved MBG - 2025

Salasova, A. & Nykjær, A. (2025). Emerging potential of progranulin-dependent SorCS2 signaling in healthy and diseased nervous systems. Neural Regeneration Research, 20(9), 2591-2593. https://doi.org/10.4103/NRR.NRR-D-24-00734

Garde, C., Pavlidis, M. A., Garces, P., Lange, E. J., Ramarathinam, S. H., Sokač, M., Pandey, K., Faridi, P., Ahrenfeldt, J., Chung, S., Friis, S., Kleine-Kohlbrecher, D., Birkbak, N. J., Kringelum, J. V., Rønø, B., Purcell, A. W. & Trolle, T. (2025). Endogenous viral elements constitute a complementary source of antigens for personalized cancer vaccines. NPJ vaccines, 10(1), Artikel 54. https://doi.org/10.1038/s41541-025-01107-y

Rasmussen, C. L. M., Frederiksen, S. F., Heegaard, C. W., Thomsen, M. S., Hede, E., Laczek, B., Körbelin, J., Wüstner, D., Thomsen, L. B., Schwaninger, M., Jensen, O. N., Moos, T. & Burkhart, A. (2025). Endothelial and neuronal engagement by AAV-BR1 gene therapy alleviates neurological symptoms and lipid deposition in a mouse model of Niemann-Pick type C2. Fluids and Barriers of the CNS, 22(1), Artikel 13. https://doi.org/10.1186/s12987-025-00621-4

Lassen, J. K. & Villesen, P. (2025). End-To-End Deep Learning Explains Antimicrobial Resistance in Peak-Picking-Free MALDI-MS Data. Analytical Chemistry, 97(5), 2795-2800. https://doi.org/10.1021/acs.analchem.4c05113

Shrestha, M., Bai, Z., Gholipourshahraki, T., Hjelholt, A. J., Hu, S., Kjolby, M., Rohde, P. D. & Sørensen, P. (2025). Enhanced genetic fine mapping accuracy with Bayesian Linear Regression models in diverse genetic architectures. PLoS Genetics, 21(7), e1011783. Artikel e1011783. https://doi.org/10.1371/journal.pgen.1011783

Charmouh, A. P., Porsborg, P. S., Hansen, L. T., Besenbacher, S., Boeg Winge, S., Almstrup, K., Hobolth, A., Bataillon, T. & Schierup, M. H. (2025). Estimating Gene Conversion Tract Length and Rate From PacBio HiFi Data. Molecular Biology and Evolution, 42(2), Artikel msaf019. https://doi.org/10.1093/molbev/msaf019

Radak, Z. & Rattan, S. I. S. (2025). Exercise, hormesis and ageing: a new section in Biogerontology. Biogerontology, 26(1), 26. Artikel 26. https://doi.org/10.1007/s10522-024-10170-2

Yuan, H., Mitchell, C. W., Ferenbach, A. T., Bonati, M. T., Feresin, A., Benke, P. J., Tan, Q. K. G. & van Aalten, D. M. F. (2025). Exploiting O-GlcNAc dyshomeostasis to screen O-GlcNAc transferase intellectual disability variants. Stem Cell Reports, 20(1), 102380. Artikel 102380. https://doi.org/10.1016/j.stemcr.2024.11.010

Stange, A. D., Zuzic, L., Schiøtt, B. & Berglund, N. A. (2025). Exploring insulin-receptor dynamics: Stability and binding mechanisms. Structure, 33(8), 1425-1435.e2. https://doi.org/10.1016/j.str.2025.04.022

Mouritzen, T. W., Meurer, K. H. E., Bornhofen, E., Janss, L., Weih, M. & Andersen, S. U. (2025). Faba bean genetics and crop growth models – progress to date and opportunities for integration. Plant and Soil, 514(1), 47-64. https://doi.org/10.1007/s11104-025-07459-7

Bontempi, D., Zalay, O., Bitterman, D. S., Birkbak, N., Shyr, D., Haugg, F., Qian, J. M., Roberts, H., Perni, S., Prudente, V., Pai, S., Dekker, A., Haibe-Kains, B., Guthier, C., Balboni, T., Warren, L., Krishan, M., Kann, B. H., Swanton, C. ... Aerts, H. J. W. L. (2025). FaceAge, a deep learning system to estimate biological age from face photographs to improve prognostication: a model development and validation study. The Lancet Digital Health, 7(6), Artikel 100870. https://doi.org/10.1016/j.landig.2025.03.002

Khachadourian, V., Arildskov, E. S., Grove, J., O'Reilly, P. F., Buxbaum, J. D., Reichenberg, A., Sandin, S., Croen, L. A., Schendel, D., Hansen, S. N. & Janecka, M. (2025). Familial confounding in the associations between maternal health and autism. Nature Medicine, 31(3), 996-1007. https://doi.org/10.1038/s41591-024-03479-5

De Dios Andres, P., Purup, A. B., Beaune, G., Timonen, J. V. I., Lyons, J. A. & Städler, B. (2025). Flippase-Mediated Hybrid Vesicle Division. Advanced Materials, 37(39), Artikel 2504519. https://doi.org/10.1002/adma.202504519

Schmidt, S. I., Okarmus, J., Madsen, D. A., Hansen, J. S., Gregersen, E., Gram, H., Winkelmann, L. S., Oliveira, A. S., Heon-Roberts, R., Ryan, B. J., Freude, K., Blaabjerg, M., Jensen, P. H. & Meyer, M. (2025). Formation of seeding-competent α-synuclein aggregates in parkin-deficient iPSC-derived human neurons. npj Parkinson's Disease , 11(1), Artikel 180. https://doi.org/10.1038/s41531-025-01038-4

Nielsen, T. T., Bali, P., Grove, J., Mohr-Jensen, C., Werge, T., Dalsgaard, S., Børglum, A. D., Sonuga-Barke, E., Minnis, H., Corfield, E. C., Tbartz van Elst, L., Mattheisen, M., de Wit, M. M., Uddin, M. J., Anney, R. J. L., Scherer, S. W., Bourgeron, T., Polderman, T. J. C., Autism Spectrum Working Group of the Psychiatric Genomics Consortium & Demontis, D. (2025). Genetic Architecture and Risk of Childhood Maltreatment Across 5 Psychiatric Diagnoses. JAMA Psychiatry, Artikel e0243639. Advance online publication. https://doi.org/10.1001/jamapsychiatry.2025.0828

Mundy, J., Hall, A. S. M., Agerbo, E., Albiñana, C., Steinbach, J., Vilhjálmsson, B. J., Østergaard, S. D. & Musliner, K. L. (2025). Genetic Confounding of the Association Between Age at First Hormonal Contraception and Depression. Acta Psychiatrica Scandinavica, 151(4), 529-536. https://doi.org/10.1111/acps.13774

Cabrejas-Olalla, A., Jørgensen, F. G., Cheng, J. Y., Kjærgaard, P. C., Schierup, M. H., Mailund, T. & Athanasiadis, G. (2025). Genetic predictions of eye and hair colour in the Danish population. Forensic Science International: Genetics, 78, Artikel 103267. https://doi.org/10.1016/j.fsigen.2025.103267

Garcia-Erill, G., Liu, S., Le, M. D., Hurley, M. M., Nguyen, H. D., Nguyen, D. Q., Nguyen, D. H., Santander, C. G., Sánchez Barreiro, F., Gomes Martins, N. F., Hanghøj, K., Salleh, F. M., Ramos-Madrigal, J., Wang, X., Sinding, M. H. S., Morales, H. E., Stæger, F. F., Wilkinson, N., Meng, G. ... Heller, R. (2025). Genomes of critically endangered saola are shaped by population structure and purging. Cell, 188(12), 3102-3116.e22. https://doi.org/10.1016/j.cell.2025.03.040

Strom, N. I., Gerring, Z. F., Galimberti, M., Yu, D., Halvorsen, M. W., Abdellaoui, A., Rodriguez-Fontenla, C., Sealock, J. M., Bigdeli, T., Coleman, J. R., Mahjani, B., Thorp, J. G., Bey, K., Burton, C. L., Luykx, J. J., Zai, G., Alemany, S., Andre, C., Askland, K. D. ... 23andMe Inc (2025). Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorder. Nature Genetics, 57(6), 1389-1401. Artikel 230. https://doi.org/10.1038/s41588-025-02189-z

Wakabayashi, T., Andersen, S. U., Tanaka, S., Sato, S., Kawaguchi, M., Kato, K. & Setoguchi, H. (2025). Genome-wide association study identifies candidate genes contributing to flowering time variation in Lotus japonicus in Japan. Plant Biotechnology, 42(1), 17-29. https://doi.org/10.5511/plantbiotechnology.24.1023a

Strom, N. I., Halvorsen, M. W., Grove, J., Ásbjörnsdóttir, B., Luðvígsson, P., Thorarensen, Ó., de Schipper, E., Bäckmann, J., Andrén, P., Tian, C., Als, T. D., Nissen, J. B., Meier, S. M., Mattheisen, M., PGC TS Working Group & 23andMe Research Team (2025). Genome-Wide Association Study Meta-Analysis of 9619 Cases With Tic Disorders. Biological Psychiatry, 97(7), 743-752. https://doi.org/10.1016/j.biopsych.2024.07.025

23andMe Research Team (2025). Genomics yields biological and phenotypic insights into bipolar disorder. Nature, 639, 968-975. Artikel 2417. https://doi.org/10.1038/s41586-024-08468-9

Qin, Q., Wei, P., Usman, S., Ahamefule, C. S., Jin, C., Wang, B., Yan, K., van Aalten, D. M. F. & Fang, W. (2025). Gfa1 (glutamine fructose-6-phosphate aminotransferase) is essential for Aspergillus fumigatus growth and virulence. BMC Biology, 23(1), Artikel 80. https://doi.org/10.1186/s12915-025-02184-0

Jin, Z., Olsen, W. P., Mörman, C., Leppert, A., Kumar, R., Møllebjerg, A., Nielsen, L. G., Moshynets, O. V., Frasinyuk, M. S., Elosua, J. Y., Ferreira, D., Abelein, A., Landreh, M., Knight, S. D., Johansson, J., Otzen, D. E. & Chen, G. (2025). Helicobacter pylori CagA protein is a potent and broad-spectrum amyloid inhibitor. Science Advances, 11(24), Artikel eads7525. https://doi.org/10.1126/sciadv.ads7525

Li, Z., Xue, Y., Duan, Y., Yuan, W., Chen, C., Shi, S., Su, X. C., Kisiswa, L., Fan, J. S. & Lin, Z. (2025). Heterotypic interactions among members of the death domain superfamily with implications for p75^NTR-mediated co-signaling. International Journal of Biological Macromolecules, 304(Part 1), Artikel 140791. https://doi.org/10.1016/j.ijbiomac.2025.140791

Andersen, H. H., Andersen, M. K., Bossow, K. A., Vestergaard, A. L., Bor, P. & Larsen, A. (2025). High-dose vitamin D supplementation in pregnancy ameliorates obesity-induced increase in maternal IL-1β level without affecting obesity-induced increase in IL-6 and MCP. The Journal of Steroid Biochemistry and Molecular Biology, 250, Artikel 106742. https://doi.org/10.1016/j.jsbmb.2025.106742

Teixeira, L. M. C., Paiva, P., Johansen, M. B., Sommerfeldt, A., Petersen, A. R., Rotilio, L., Sandahl, A., Morth, J. P., Westh, P., Otzen, D. E., Fernandes, P. A. & Ramos, M. J. (2025). Hydrolysis of the Urethane Bond Catalyzed by Pseudomonas sp. MIS38 Lipase: A QM/MM Mechanistic Insight. ACS Catalysis, 15, 14728-14740. https://doi.org/10.1021/acscatal.5c03228

Pareek, C. S., Sachajko, M., Kalra, G., Sultana, S., Szostak, A., Chalaskiewicz, K., Kepka-Borkowska, K., Poławska, E., Ogłuszka, M., Pierzchała, D., Starzyński, R., Taniguchi, H., Juszczuk-Kubiak, E., Lepczyński, A., Ślaska, B., Kozera, W., Czarnik, U., Wysocki, P., Kadarmideen, H. N. ... Pierzchała, M. (2025). Identification of trait-associated microRNA modules in liver transcriptome of pig fed with PUFAs-enriched supplementary diet. Journal of Applied Genetics, 66(2), 389-407. https://doi.org/10.1007/s13353-024-00912-w

Peña-Díaz, S., Manglano-Artuñedo, Z., Pinheiro, F. & Ventura, S. (2025). Identification of α-Synuclein Aggregation Inhibitors via High-Throughput Screening. I Neuromethods (s. 61-85). The Humana Press Inc.. https://doi.org/10.1007/978-1-0716-4232-0_3

Li, Q., Marietou, A., Andersen, F. F., Hosek, J., Scavenius, C., Zhang, J. & Schwab, C. (2025). In vitro investigations on the impact of fermented dairy constituents on fecal microbiota composition and fermentation activity. Microbiology Spectrum, 13(3), e0219324. https://doi.org/10.1128/spectrum.02193-24

TRACERx Consortium & Genomics England Consortium (2025). ImmuneLENS characterizes systemic immune dysregulation in aging and cancer. Nature Genetics, 57(3), 694-705. Artikel 305. https://doi.org/10.1038/s41588-025-02086-5

Dardani, C., Robinson, J. W., Jones, H. J., Rai, D., Stergiakouli, E., Grove, J., Gardner, R., McIntosh, A. M., Havdahl, A., Hemani, G., Davey Smith, G., Richardson, T. G., Gaunt, T. R. & Khandaker, G. M. (2025). Immunological drivers and potential novel drug targets for major psychiatric, neurodevelopmental, and neurodegenerative conditions. Molecular Psychiatry, 30(10), 4487-4496. Artikel e1004092. https://doi.org/10.1038/s41380-025-03032-x

Huang, Z., Pych, E., Whitehead, B. J., Nejsum, P. L., Bellini, I., Drace, T., Boesen, T., Paponov, I. & Rasmussen, M. K. (2025). Impact of abiotic stress on miRNA profiles in tomato-derived extracellular vesicles and their biological activity. International Journal of Biological Macromolecules, 319, Artikel 145260. https://doi.org/10.1016/j.ijbiomac.2025.145260

Bruhn, D., Fan, Y., Griffin, K. L., Cowan-Turner, D., Scafaro, A. P., Møller, I. M. & Atkin, O. K. (2025). Importance of the leaf respiratory quotient. Physiologia Plantarum, 177(2), Artikel e70235. https://doi.org/10.1111/ppl.70235

Bruhn, D., Griffin, K. L. & Møller, I. M. (2025). Importance of Timing of Dark Acclimation for Estimating Light Inhibition of Leaf Respiratory CO₂ Efflux. Plant, Cell & Environment, 48(5), 3151-3158. https://doi.org/10.1111/pce.15335

Midtgaard, S. R., Hansen, M. S., Drachmann, N., Geng, X., Blans, K. I. M., Møbjerg, M. M. F., Frølund, A. F., Rasmussen, J. T. & Ostenfeld, M. S. (2025). Industrial Scale Production and Characterization of a Whey Fraction Enriched in Extracellular Vesicle Material. Journal of Extracellular Biology, 4(5), Artikel e70044. https://doi.org/10.1002/jex2.70044

Sendrowski, J., Bataillon, T. & Ramstein, G. P. (2025). In silico prediction of variant effects: promises and limitations for precision plant breeding. Theoretical and Applied Genetics, 138(8), Artikel 193. https://doi.org/10.1007/s00122-025-04973-1

Wang, J., Kidmose, R. T., Boegholm, N., Zacharia, N. K., Thomsen, M. B., Christensen, A., Malik, T., Lechtreck, K. & Lorentzen, E. (2025). Integrative in silico and biochemical analyses demonstrate direct Arl3-mediated ODA16 release from the intraflagellar transport machinery. Journal of Biological Chemistry, 301(3), Artikel 108237. https://doi.org/10.1016/j.jbc.2025.108237

Garland, W. & Jensen, T. H. (2025). Integrator: A guardian against RNA-induced chaos. Cell Chemical Biology, 32(6), 780-782. https://doi.org/10.1016/j.chembiol.2025.05.009

Otzen, D. E., Peña-Díaz, S., Widmann, J., Daugberg, A. O. H., Zhang, Z., Jiang, Y., Mittal, C., Dueholm, M. K. D., Louros, N., Wang, H. & Javed, I. (2025). Interactions between pathological and functional amyloid: A match made in Heaven or Hell? Molecular Aspects of Medicine, 103, 101351. Artikel 101351. https://doi.org/10.1016/j.mam.2025.101351

Yadav, S. K., Kidmose, R. T. & Lorentzen, E. (2025). Intraflagellar transport: How kinesin motors hook onto their trains. Current biology : CB, 35(19), R928-R931. https://doi.org/10.1016/j.cub.2025.08.049

Olsen, W. P., Larsen, A.-K. K., Christensen, J. L., Malle, M. G. & Otzen, D. E. (2025). Investigating strategies for creating cross-linked amyloid fibril networks through branching of amyloid growth. Colloids and surfaces. B, Biointerfaces, 251, 114617. Artikel 114617. https://doi.org/10.1016/j.colsurfb.2025.114617

López Hernández, M., Otzen, D. E. & Pedersen, J. S. (2025). Investigating the interactions between an industrial lipase and anionic (bio)surfactants. Journal of Colloid and Interface Science, 679(B), 294-306. https://doi.org/10.1016/j.jcis.2024.10.060

Garcia-Morena, D., Fernandez-Cantos, M. V., Escalera, S. L., Lok, J., Iannone, V., Cancellieri, P., Maathuis, W., Panagiotou, G., Aranzamendi, C., Aidy, S. E., Kolehmainen, M., El-Nezami, H., Wellejus, A. & Kuipers, O. P. (2025). In Vitro Influence of Specific Bacteroidales Strains on Gut and Liver Health Related to Metabolic Dysfunction-Associated Fatty Liver Disease. Probiotics and antimicrobial proteins, 17(3), 1498-1512. Artikel 101314. https://doi.org/10.1007/s12602-024-10219-1

Behrens, T., Balasubramanian, J., Ivask, M., Nõmm, M., Kavak, A., Secher, J. B.-M., Kadarmideen, H. N. & Rabaglino, M. B. (2025). In vitro processes alter the embryonic disc epigenome and transcriptome in the pre-implantation elongated bovine embryo. Biology of Reproduction, Artikel ioaf095. Advance online publication. https://doi.org/10.1093/biolre/ioaf095

Nazari, M., Korshj, A. R. & Rehman, N. U. (2025). Jump Plus AM-FM Mode Decomposition. IEEE Transactions on Signal Processing, 73, 1081-1093. https://doi.org/10.1109/TSP.2025.3535822

Kjær, A., Kristjánsdóttir, N., Juul, R. I., Nordentoft, I., Birkenkamp-Demtröder, K., Ahrenfeldt, J., Strandgaard, T., Radif, D., Hodgson, D., Abbosh, C., Aerts, H. J. W. L., Agerbæk, M., Jensen, J. B., Birkbak, N. J. & Dyrskjøt, L. (2025). Low T cell diversity associates with poor outcome in bladder cancer: A comprehensive longitudinal analysis of the T cell receptor repertoire. Cell Reports Medicine, 6(5), Artikel 102101. https://doi.org/10.1016/j.xcrm.2025.102101

Rasmussen, M. Q., Bønnelykke-Behrndtz, M. L., Merrild, C., Tvilling, I. K. S., Christensen, J. N., Nielsen, M. M., Georgsen, J. B., Naumann, N., Gudbergsson, J. M., Etzerodt, A., Pedersen, J. S., Jenkins, R. W., Degn, S. E., Moestrup, S. K., Schmidt, H., Steiniche, T. & Madsen, M. (2025). LRP2 Expression in Melanoma Is Associated With a Transitory Cell State, Increased T Cell Infiltration, and Is Upregulated by IFNy Signaling. Pigment Cell & Melanoma Research, 38(5), Artikel e70053. https://doi.org/10.1111/pcmr.70053

Morin, M., Yin, W., MacLean, H., Devlin, B., Reichenberg, A., Swan, S. H., Buxbaum, J. D., Schendel, D., Persson, M., Laursen, T. M., Kolevzon, A., Grove, J., Klei, L., Roeder, K. & Sandin, S. (2025). Maternal body mass index in early pregnancy and autism in offspring: a population-based cohort study in Sweden and Denmark. BMC Medicine, 23(1), 620. https://doi.org/10.1186/s12916-025-04487-z

Buhl, E. H., Christensen, B., Pedersen, F. H. & S⊘rensen, E. S. (2025). Milk osteopontin has high iron-binding capacity and facilitates iron absorption in intestinal cells. Journal of Dairy Science, 108(1), 90-100. https://doi.org/10.3168/jds.2024-25305

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Behrens, T., Balasubramanian, J., Secher, J. B.-M., Ivask, M., Kadarmideen, H. & Rabaglino, M. (2025). Effects of in vitro embryo production on the epigenomic profiles of day 15 bovine conceptus. Reproduction, Fertility and Development, 37(1), Artikel 114. https://doi.org/10.1071/RDv37n1Ab114

Radak, Z. & Rattan, S. I. S. (2025). Exercise, hormesis and ageing: a new section in Biogerontology. Biogerontology, 26(1), 26. Artikel 26. https://doi.org/10.1007/s10522-024-10170-2

23andMe Research Team (2025). Genomics yields biological and phenotypic insights into bipolar disorder. Nature, 639, 968-975. Artikel 2417. https://doi.org/10.1038/s41586-024-08468-9

Garland, W. & Jensen, T. H. (2025). Integrator: A guardian against RNA-induced chaos. Cell Chemical Biology, 32(6), 780-782. https://doi.org/10.1016/j.chembiol.2025.05.009

Nazari, M., Korshj, A. R. & Rehman, N. U. (2025). Jump Plus AM-FM Mode Decomposition. IEEE Transactions on Signal Processing, 73, 1081-1093. https://doi.org/10.1109/TSP.2025.3535822

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Revideret 02.12.2024

Lisbeth Heilesen