Yuan, H., Mitchell, C. W., Ferenbach, A. T., Bonati, M. T., Feresin, A., Benke, P. J., Tan, Q. K. G.
& van Aalten, D. M. F. (2025).
Exploiting O-GlcNAc dyshomeostasis to screen O-GlcNAc transferase intellectual disability variants.
Stem Cell Reports,
20(1), 102380. Artikel 102380.
https://doi.org/10.1016/j.stemcr.2024.11.010
Wang, J., Kidmose, R. T., Boegholm, N., Zacharia, N. K., Thomsen, M. B., Christensen, A., Malik, T., Lechtreck, K.
& Lorentzen, E. (2025).
Integrative in silico and biochemical analyses demonstrate direct Arl3-mediated ODA16 release from the intraflagellar transport machinery.
Journal of Biological Chemistry,
301(3), Artikel 108237.
https://doi.org/10.1016/j.jbc.2025.108237
Wakabayashi, T.
, Andersen, S. U., Tanaka, S., Sato, S., Kawaguchi, M., Kato, K. & Setoguchi, H. (2025).
Genome-wide association study identifies candidate genes contributing to flowering time variation in Lotus japonicus in Japan.
Plant Biotechnology,
42(1), 17-29.
https://doi.org/10.5511/plantbiotechnology.24.1023a
Thorsen, T. S., Kulkarni, Y., Sykes, D. A.
, Bøggild, A., Drace, T., Hompluem, P., Iliopoulos-Tsoutsouvas, C., Nikas, S. P., Daver, H., Makriyannis, A.
, Nissen, P., Gajhede, M., Veprintsev, D. B.
, Boesen, T., Kastrup, J. S. & Gloriam, D. E. (2025).
Structural basis of THC analog activity at the Cannabinoid 1 receptor.
Nature Communications,
16(1), Artikel 486.
https://doi.org/10.1038/s41467-024-55808-4
Theologidis, V., Ferreira, S. A., Jensen, N. M., Gomes Moreira, D., Ahlgreen, O. A., Hansen, M. W., Rosenberg, E. D., Richner, M., Faress, I., Gram, H., Jensen, P. H., Borghammer, P., Nyengaard, J. R., Romero-Ramos, M., Vægter, C. B., van de Berg, W. D. J.
, Van Den Berge, N. & Jan, A. (2025).
Bradykinesia and postural instability in a model of prodromal synucleinopathy with α-synuclein aggregation initiated in the gigantocellular nuclei.
Acta Neuropathologica Communications,
13(1), 32. Artikel 32.
https://doi.org/10.1186/s40478-025-01948-7
Subrahmaniam, H. J., Pico, X.
, Bataillon, T., Salomonsen, C. L., Glasius, M. & Ehlers, B. (2025).
Natural variation in root exudate composition in the genetically structured Arabidopsis thaliana in the Iberian Peninsula.
New Phytologist,
245(4), 1437-1449.
https://doi.org/10.1111/nph.20314
Staehr, C., Login, H., Melnikova, E., Bakun, M., Ziemlinska, E.
, Kisiswa, L., Berenji Ardestani, S., Nolte, S. S., Beck, H. C.
, Hansen, L. M. B., Postnov, D., Verkhratsky, A., Malik, A. R.
, Nykjær, A. & Matchkov, V. (2025).
SorCS2 Is Important for Astrocytic Function in Neurovascular Signaling.
Acta Physiologica (Print),
241(6).
https://doi.org/10.1111/apha.70052
Singh, P., Kadam, N. Y., Panigrahi, R., Mehrotra, A., Upadhayay, K., Dey, M., Tyagi, A., Aquib, M.
, Nielsen, J., Kleijwegt, G., Singh, P., Sharma, A., Rao, A.
, Otzen, D. E., Kumar, A. & Sharma, D. (2025).
Sulfamerazine as a Potential Modulator against α-Synuclein Aggregation and Associated Toxicity.
ACS Chemical Neuroscience,
16(5), 880-894.
https://doi.org/10.1021/acschemneuro.4c00803
Simonsen, B., Rübsam, H., Kolte, M. V., Larsen, M. M., Krönauer, C., Gysel, K., Laursen, M., Feng, F.
, Sezer, G., Oldroyd, G. E. D.
, Stougaard, J., Fort, S.
, Radutoiu, S. & Andersen, K. R. (2025).
The Medicago truncatula LYR4 intracellular domain serves as a scaffold in immunity signaling independent of its phosphorylation activity.
New Phytologist. Advance online publication.
https://doi.org/10.1111/nph.70067
Simonsen, B., Rübsam, H., Kolte, M. V., Larsen, M. M., Krönauer, C., Gysel, K., Laursen, M., Feng, F., Kaya, G., Oldroyd, G. E. D.
, Stougaard, J., Fort, S.
, Radutoiu, S. & Andersen, K. R. (2025).
The Medicago truncatula LYR4 intracellular domain serves as a scaffold in immunity signaling independent of its phosphorylation activity.
New Phytologist,
246(4), 1423-1431.
https://doi.org/10.1111/nph.70067
Shiraz, M. G., Nielsen, J., Widmann, J., Chung, K. H. K., Davis, T. P.
, Rasmussen, C., Scavenius, C., Enghild, J. J., Martin-Gallausiaux, C., Singh, Y., Javed, I.
& Otzen, D. E. (2025).
Young rat microbiota extracts strongly inhibit fibrillation of α-synuclein and protect neuroblastoma cells and zebrafish against α-synuclein toxicity.
Molecules and Cells,
48(1), Artikel 100161.
https://doi.org/10.1016/j.mocell.2024.100161
Shah, A., Zhang, X., Snee, M., Lockhart-Cairns, M. P., Levy, C. W., Jowitt, T. A., Birchenough, H. L., Dean, L., Collins, R., Dodd, R. J., Roberts, A. R. E.
, Enghild, J. J., Mantovani, A., Fontana, J., Baldock, C., Inforzato, A., Richter, R. P. & Day, A. J. (2025).
The structural organisation of pentraxin-3 and its interactions with heavy chains of inter-α-inhibitor regulate crosslinking of the hyaluronan matrix.
Matrix biology : journal of the International Society for Matrix Biology,
136, 52-68.
https://doi.org/10.1016/j.matbio.2025.01.002
Schulz, L.
, Ung, K. L., Zuzic, L., Koutnik-Abele, S.
, Schiøtt, B., Stokes, D. L., Pedersen, B. P. & Hammes, U. Z. (2025).
Transport of phenoxyacetic acid herbicides by PIN-FORMED auxin transporters.
Nature Plants. Advance online publication.
https://doi.org/10.1038/s41477-025-01984-0
Schlosser, A., Pilecki, B., Allen, C., Benest, A. V., Lynch, A. P., Hua, J., Ved, N., Blackley, Z., Andersen, T. L., Hennig, D., Graversen, J. H., Möller, S., Skallerup, S., Ormhøj, M., Lange, C., Agostini, H. T., Grauslund, J., Heegaard, S., Dacheva, I. ... Sorensen, G. L. (2025).
Pharmacological blocking of microfibrillar-associated protein 4 reduces retinal neoangiogenesis and vascular leakage.
Molecular Therapy,
33(3), 1048-1072.
https://doi.org/10.1016/j.ymthe.2025.01.038
Sall, K. K.
, Foldager, L., Delf, C., Christensen, S. J., Agerley, M. N., Havn, K. T. & Pedersen, C. (2025).
Control of neonatal diarrhea in piglets with reduced antibiotic use by application of a complementary feed - a randomized controlled farm trial.
Veterinary Sciences,
12(1), Artikel 42.
https://doi.org/10.3390/vetsci12010042
Rotilio, L., Bayer, T., Meinert, H., Teixeira, L. M. C., Johansen, M. B., Sommerfeldt, A., Petersen, A. R., Sandahl, A., Keller, M. B., Holck, J., Paiva, P.
, Otzen, D. E., Bornscheuer, U. T., Wei, R., Fernandes, P. A., Ramos, M. J., Westh, P. & Morth, J. P. (2025).
Structural and Functional Characterization of an Amidase Targeting a Polyurethane for Sustainable Recycling.
Angewandte Chemie International Edition,
64(7), Artikel e202419535.
https://doi.org/10.1002/anie.202419535
Riedelbauch, S., Masser, S., Fasching, S., Lin, S. Y., Salgania, H. K.
, Aarup, M., Ebert, A., Jeske, M., Levine, M. T., Stelzl, U.
& Andersen, P. (2025).
Recurrent innovation of protein-protein interactions in the Drosophila piRNA pathway.
EMBO Journal, Artikel 98. Advance online publication.
https://doi.org/10.1038/s44318-025-00439-8
Rasmussen, C. L. M., Frederiksen, S. F.
, Heegaard, C. W., Thomsen, M. S., Hede, E., Laczek, B., Körbelin, J., Wüstner, D., Thomsen, L. B., Schwaninger, M., Jensen, O. N., Moos, T. & Burkhart, A. (2025).
Endothelial and neuronal engagement by AAV-BR1 gene therapy alleviates neurological symptoms and lipid deposition in a mouse model of Niemann-Pick type C2.
Fluids and Barriers of the CNS,
22(1), Artikel 13.
https://doi.org/10.1186/s12987-025-00621-4
Rashidi, A.
, Füchtbauer, E. M., Vahabzadeh, Z., Soleimani, F., Rahimi, K., Nikkhoo, B., Fakhari, S., Erfan, M. B. K., Azarnezhad, A., Pooladi, A., Soheili, F. & Fathi, F. (2025).
CRISPR/Cas9-mediated knockout of DYRK1B in triple-negative breast cancer cells: implications for cell proliferation, apoptosis, and therapeutic sensitivity.
Biochemical Engineering Journal,
213, Artikel 109553.
https://doi.org/10.1016/j.bej.2024.109553
Qin, Q., Wei, P., Usman, S., Ahamefule, C. S., Jin, C., Wang, B., Yan, K.
, van Aalten, D. M. F. & Fang, W. (2025).
Gfa1 (glutamine fructose-6-phosphate aminotransferase) is essential for Aspergillus fumigatus growth and virulence.
BMC Biology,
23(1), Artikel 80.
https://doi.org/10.1186/s12915-025-02184-0
Prip, F., Lamy, P., Lindskrog, S. V., Strandgaard, T., Nordentoft, I., Birkenkamp-Demtröder, K., Birkbak, N. J., Kristjánsdóttir, N., Kjær, A., Andreasen, T. G., Ahrenfeldt, J., Pedersen, J. S., Rasmussen, A. M., Hermann, G. G., Mogensen, K., Petersen, A. C., Hartmann, A., Grimm, M. O., Horstmann, M. ... UROMOL Consortium (2025).
Comprehensive genomic characterization of early-stage bladder cancer.
Nature Genetics,
57(1), 115-125. Artikel 2301.
https://doi.org/10.1038/s41588-024-02030-z
Paiva, P., Teixeira, L. M. C., Wei, R., Liu, W., Weber, G., Morth, J. P., Westh, P., Petersen, A. R., Johansen, M. B., Sommerfeldt, A., Sandahl, A.
, Otzen, D. E., Fernandes, P. A. & Ramos, M. J. (2025).
Unveiling the enzymatic pathway of UMG-SP2 urethanase: insights into polyurethane degradation at the atomic level.
Chemical Science,
16(5), 2437-2452.
https://doi.org/10.1039/d4sc06688j
Otzen, D. E., Peña-Díaz, S., Widmann, J., Daugberg, A. O. H.
, Zhang, Z., Jiang, Y., Mittal, C., Dueholm, M. K. D., Louros, N., Wang, H. & Javed, I. (2025).
Interactions between pathological and functional amyloid: A match made in Heaven or Hell? Molecular Aspects of Medicine,
103, 101351. Artikel 101351. Advance online publication.
https://doi.org/10.1016/j.mam.2025.101351
Olsen, W. P., Larsen, A.-K. K., Christensen, J. L.
, Malle, M. G. & Otzen, D. E. (2025).
Investigating strategies for creating cross-linked amyloid fibril networks through branching of amyloid growth.
Colloids and surfaces. B, Biointerfaces,
251, 114617. Artikel 114617. Advance online publication.
https://doi.org/10.1016/j.colsurfb.2025.114617
O’Leary, E.
, Jiang, Y., Kristensen, L. S., Hansen, T. B.
& Kjems, J. (2025).
The therapeutic potential of circular RNAs.
Nature Reviews Genetics,
26(4), 230-244. Artikel 2629.
https://doi.org/10.1038/s41576-024-00806-x
Nybo, T., Gamon, L. F., Fuentes-Lemus, E.
, Otzen, D. E., Davies, M. J. & Hägglund, P. (2025).
Dimethyl labeling of N-terminal amines allows unambiguous identification of protein crosslinks.
Free Radical Biology & Medicine,
227, 629-637.
https://doi.org/10.1016/j.freeradbiomed.2024.12.002
Nowak, J. S., Olesen, S., Tian, P.
, Bærentsen, R. L., Brodersen, D. E. & Otzen, D. E. (2025).
Role of electrostatics in cold adaptation: A comparative study of eury- and stenopsychrophilic triose phosphate isomerase.
B B A - Proteins and Proteomics,
1873(4), Artikel 141072.
https://doi.org/10.1016/j.bbapap.2025.141072
Nowak, J. S., Kruuse, N., Rasmussen, H. Ø., Tian, P.
, Astono, J., Schultz-Nielsen, S.
, Thøgersen, M. S., Stougaard, P., Pedersen, J. S. & Otzen, D. E. (2025).
Quaternary stabilization of a GH2 β-galactosidase from the psychrophile A. ikkensis, a flexible and unstable dimeric enzyme.
Protein Science,
34(5).
https://doi.org/10.1002/pro.70141
Nel, L., Thaysen, K., Jamecna, D.
, Olesen, E., Langer, J.
, Frain, K. M., Szomek, M., Höglinger, D., Wüstner, D.
& Pedersen, B. P. (2025).
Structural and biochemical analysis of ligand binding in yeast Niemann–Pick type C1–related protein.
Life Science Alliance,
8(1), Artikel e202402990.
https://doi.org/10.26508/lsa.202402990
Mundy, J., Hall, A. S. M., Agerbo, E., Albiñana, C., Steinbach, J., Vilhjálmsson, B. J., Østergaard, S. D. & Musliner, K. L. (2025).
Genetic Confounding of the Association Between Age at First Hormonal Contraception and Depression.
Acta Psychiatrica Scandinavica,
151(4), 529-536.
https://doi.org/10.1111/acps.13774
Mouritzen, T. W., Meurer, K. H. E.
, Bornhofen, E., Janss, L., Weih, M.
& Andersen, S. U. (2025).
Faba bean genetics and crop growth models – progress to date and opportunities for integration.
Plant and Soil. Advance online publication.
https://doi.org/10.1007/s11104-025-07459-7
Midtgaard, S. R., Hansen, M. S., Drachmann, N., Geng, X., Blans, K. I. M., Møbjerg, M. M. F., Frølund, A. F.
, Rasmussen, J. T. & Ostenfeld, M. S. (2025).
Industrial Scale Production and Characterization of a Whey Fraction Enriched in Extracellular Vesicle Material.
Journal of Extracellular Biology,
4(5), Artikel e70044.
https://doi.org/10.1002/jex2.70044
McLain, A., Kowalczyk, A., Baran-Rachwalska, P., Sutera, F. M., Robertson, L. J.
, Nielsen, N. S., Enghild, J. J., Cobice, D., Bonelli, F., Barbaro, V., Ferrari, S., Patterson, B., Moore, L., Marshall, J., Nesbit, M. A. & Moore, T. (2025).
TGFBI R124H mutant allele silencing in granular corneal dystrophy type 2 using topical siRNA delivery.
Journal of Controlled Release,
382, Artikel 113681.
https://doi.org/10.1016/j.jconrel.2025.113681
Marzookian, K.
, Aliakbari, F., Hourfar, H., Sabouni, F.
, Otzen, D. E. & Morshedi, D. (2025).
The neuroprotective effect of human umbilical cord MSCs-derived secretome against α-synuclein aggregates on the blood-brain barrier.
International Journal of Biological Macromolecules,
304(Part 1), Artikel 140387.
https://doi.org/10.1016/j.ijbiomac.2025.140387
Martín-Rivada, Á., Martos-Moreno, G., Guerra-Cantera, S., Campillo-Calatayud, A.
, Oxvig, C., Frystyk, J., Chowen, J. A., Barrios, V. & Argente, J. (2025).
Prepubertal Children With Obesity Have High Free IGF-1 Levels and Accelerated Growth Despite Reduced Pappalysin Levels.
Journal of Clinical Endocrinology and Metabolism,
110(3), e622-e629.
https://doi.org/10.1210/clinem/dgae288
Malham, M., Vestergaard, M. V.
, Bataillon, T., Villesen, P., Dempfle, A., Bang, C., Engsbro, A. L., Jakobsen, C., Franke, A., Wewer, V.
, Thingholm, L. B. & Petersen, A. M. (2025).
The Composition of the Fecal and Mucosa-adherent Microbiota Varies Based on Age and Disease Activity in Ulcerative Colitis.
Inflammatory Bowel Diseases,
31(2), 501-513.
https://doi.org/10.1093/ibd/izae179
Ma, J., Bechsgaard, J. S., Lauridsen, A. A., Villesen, P., Bilde, T. & Schierup, M. H. (2025).
The genomic consequences and persistence of sociality in spiders.
Genome Research,
35(3), 499-511.
https://doi.org/10.1101/gr.279503.124
Li, Q., Marietou, A., Andersen, F. F.
, Hosek, J., Scavenius, C., Zhang, J.
& Schwab, C. (2025).
In vitro investigations on the impact of fermented dairy constituents on fecal microbiota composition and fermentation activity. Microbiology Spectrum,
13(3), e0219324.
https://doi.org/10.1128/spectrum.02193-24
Li, Z., Xue, Y., Duan, Y., Yuan, W., Chen, C., Shi, S., Su, X. C.
, Kisiswa, L., Fan, J. S. & Lin, Z. (2025).
Heterotypic interactions among members of the death domain superfamily with implications for p75NTR-mediated co-signaling.
International Journal of Biological Macromolecules,
304(Part 1), Artikel 140791.
https://doi.org/10.1016/j.ijbiomac.2025.140791
Kriebisch, C. M. E., Bantysh, O.
, Baranda Pellejero, L., Belluati, A., Bertosin, E., Dai, K., de Roy, M., Fu, H., Galvanetto, N., Gibbs, J. M., Gomez, S. S., Granatelli, G., Griffo, A., Guix, M., Gurdap, C. O., Harth-Kitzerow, J., Haugerud, I. S., Häfner, G., Jaiswal, P. ... Boekhoven, J. (2025).
A roadmap toward the synthesis of life.
Chem,
11(3), Artikel 102399.
https://doi.org/10.1016/j.chempr.2024.102399