New publication
Discovery of the tPAF complex in our lab's first publication!
8. October, 2024:
Major milestone: our lab's first paper from our first PhD student, Astrid Pold Vilstrup is now published! We discovered that developing sperm cells in fruit flies use their own private version of a universal gene-reading machine. This testis-specific complex, called tPAF, is built from duplicate copies of a well-known transcription regulator and turns out to be essential for properly shutting down genes at the right spot. Without it, transcription runs off-track into neighboring genes, expression of key fertility genes on the Y chromosome falters, and cell division goes haywire — making the flies completely sterile. Reads all about it in Genes & Development.
