Department of Molecular Biology and Genetics

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 Department of Molecular Biology and Genetics Research Research areas Neurobiology Gilles Vanwalleghem

Gilles Vanwalleghem
[Translate to English:] Legend: The six days old larval zebrafish expresses a fluorescent calcium reporter in all of its neurons, including in the enteric nervous system that regulates the gut. We use this transparent animal to image in vivo the activity of its neurons. Arrows indicate the rostral, dorsal, caudal, and ventral directions. Scale bar is 100 um.
Video legend: Live imaging of the activity of neurons in the guts of a six days old larval zebrafish, we can see the high motility of the guts driven by the waves of neuronal activity.

Featured articles

  • “Brain-wide mapping of water flow perception in zebrafish.” Vanwalleghem G, Schuster K, Taylor MA, Favre-Bulle IA, Scott EK. Journal of Neuroscience, doi: 10.1523/JNEUROSCI.0049-20.2020 (2020)
  • “Cellular resolution imaging of vestibular processing across the larval zebrafish brain” Favre-Bulle IA*, Vanwalleghem GC*, Taylor MA, Rubinsztein-Dunlop H, Scott EK. Current Biology. doi: 10.1016/j.cub.2018.09.060. (2018)
  • “Integrative whole-brain neuroscience in larval zebrafish" Vanwalleghem G, Ahrens MB and Scott EK. Current Opinion in Neurobiology. doi: 10.1016/j.conb.2018.02.004 (2018)

Peer-reviewed publications

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Vanwalleghem, G., Schuster, K., Taylor, M. A., Favre-Bulle, I. A. & Scott, E. K. (2020). Brain-wide mapping of water flow perception in zebrafish. Journal of Neuroscience, 40(21), 4130-4144. https://doi.org/10.1523/JNEUROSCI.0049-20.2020
Wong, E. S., Zheng, D., Tan, S. Z., Bower, N. I., Garside, V., Vanwalleghem, G., Gaiti, F., Scott, E., Hogan, B. M., Kikuchi, K., McGlinn, E., Francois, M. & Degnan, B. M. (2020). Deep conservation of the enhancer regulatory code in animals. Science, 370(6517), Article eaax8137. https://doi.org/10.1126/science.aax8137
Stevenson, A. J., Vanwalleghem, G., Stewart, T. A., Condon, N. D., Lloyd-Lewis, B., Marino, N., Putney, J. W., Scott, E. K., Ewing, A. D. & Davis, F. M. (2020). Multiscale imaging of basal cell dynamics in the functionally mature mammary gland. Proceedings of the National Academy of Sciences (PNAS), 117(43), 26822-26832. https://doi.org/10.1073/pnas.2016905117
Favre-Bulle, I. A., Taylor, M. A., Marquez-Legorreta, E., Vanwalleghem, G., Poulsen, R. E., Rubinsztein-Dunlop, H. & Scott, E. K. (2020). Sound generation in zebrafish with Bio-Opto-Acoustics. Nature Communications, 11(1), Article 6120. https://doi.org/10.1038/s41467-020-19982-5
Lecordier, L., Uzureau, S., Vanwalleghem, G., Deleu, M., Crowet, J. M., Barry, P., Moran, B., Voorheis, P., Dumitru, A. C., Yamaryo-Botté, Y., Dieu, M., Tebabi, P., Vanhollebeke, B., Lins, L., Botté, C. Y., Alsteens, D., Dufrêne, Y., Pérez-Morga, D., Nolan, D. P. & Pays, E. (2020). The Trypanosoma Brucei KIFC1 Kinesin Ensures the Fast Antibody Clearance Required for Parasite Infectivity. iScience, 23(9), Article 101476. https://doi.org/10.1016/j.isci.2020.101476

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Revised 13.11.2025