Department of Molecular Biology and Genetics

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 Department of Molecular Biology and Genetics Research Research areas Neurobiology Gilles Vanwalleghem

Gilles Vanwalleghem
[Translate to English:] Legend: The six days old larval zebrafish expresses a fluorescent calcium reporter in all of its neurons, including in the enteric nervous system that regulates the gut. We use this transparent animal to image in vivo the activity of its neurons. Arrows indicate the rostral, dorsal, caudal, and ventral directions. Scale bar is 100 um.
Video legend: Live imaging of the activity of neurons in the guts of a six days old larval zebrafish, we can see the high motility of the guts driven by the waves of neuronal activity.

Featured articles

  • “Brain-wide mapping of water flow perception in zebrafish.” Vanwalleghem G, Schuster K, Taylor MA, Favre-Bulle IA, Scott EK. Journal of Neuroscience, doi: 10.1523/JNEUROSCI.0049-20.2020 (2020)
  • “Cellular resolution imaging of vestibular processing across the larval zebrafish brain” Favre-Bulle IA*, Vanwalleghem GC*, Taylor MA, Rubinsztein-Dunlop H, Scott EK. Current Biology. doi: 10.1016/j.cub.2018.09.060. (2018)
  • “Integrative whole-brain neuroscience in larval zebrafish" Vanwalleghem G, Ahrens MB and Scott EK. Current Opinion in Neurobiology. doi: 10.1016/j.conb.2018.02.004 (2018)

Peer-reviewed publications

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Favre-Bulle, I. A., Vanwalleghem, G., Taylor, M. A., Rubinsztein-Dunlop, H. & Scott, E. K. (2018). Cellular-Resolution Imaging of Vestibular Processing across the Larval Zebrafish Brain. Current Biology, 28(23), 3711-3722.e3. https://doi.org/10.1016/j.cub.2018.09.060
Taylor, M. A., Vanwalleghem, G. C., Favre-Bulle, I. A. & Scott, E. K. (2018). Diffuse light-sheet microscopy for stripe-free calcium imaging of neural populations. journal of biophotonics, 11(12), Article e201800088. https://doi.org/10.1002/jbio.201800088
Heap, L. A., Vanwalleghem, G. C., Thompson, A. W., Favre-Bulle, I., Rubinsztein-Dunlop, H. & Scott, E. K. (2018). Hypothalamic projections to the optic tectum in larval zebrafish. Frontiers in Neuroanatomy, 11, Article 135. https://doi.org/10.3389/fnana.2017.00135
Vanwalleghem, G. C., Ahrens, M. B. & Scott, E. K. (2018). Integrative whole-brain neuroscience in larval zebrafish. Current Opinion in Neurobiology, 50, 136-145. https://doi.org/10.1016/j.conb.2018.02.004
Heap, L. A. L., Vanwalleghem, G., Thompson, A. W., Favre-Bulle, I. A. & Scott, E. K. (2018). Luminance Changes Drive Directional Startle through a Thalamic Pathway. Neuron, 99(2), 293-301.e4. https://doi.org/10.1016/j.neuron.2018.06.013

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Revised 13.11.2025
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Lisbeth Heilesen