New insights into how the CRISPR immune system evolved

With new insights into how the genetic tool CRISPR – which allows direct editing of our genes – evolved and adapted, we are now one step closer to understanding the basis of the constant struggle for survival that takes place in nature. The results can be used in future biotechnologies.

Researchers reveal how bacteria can adapt to resist treatment by antibiotics

In a joint collaboration, researchers from Denmark and Switzerland have shown that bacteria produce a specific stress molecule, divide more slowly, and thus save energy when they are exposed to antibiotics. The new knowledge is expected to form the basis for development of a new type of antibiotics.

Arms race among microbes

The hot, muddy pools of Iceland are home to a number of simple, single-celled organisms, and new research shows that they also constitute a true biological battlefield and the basis for an arms race of unprecedented magnitude. The new knowledge about the struggle between living organisms in hot pools gives us a much better understanding of how  microorganisms survive when exposed to stress, information which could be used for the development of future drugs.

Danish researchers reveal how the MRSA bacterium handles stress

An international team of researchers has revealed a fundamental mechanism responsible for handling stress in staphylococci when they are exposed to antibiotics. It is expected that the research results eventually can be used to develop new antibiotics that circumvent such stress mechanisms.

Bacteria’s secret weapon against pesticides and antibiotics revealed

Bacteria exhibit extreme adaptability, which makes them capable of surviving in the most inhospitable conditions. New research results produced by Danish and British researchers now reveal the molecular details behind one of the secret weapons used by bacteria in their battle to survive under very nutrient-poor and even toxic conditions.

Læs mere om forskningsresultaterne.

X-rays reveal the self-defence mechanisms of bacteria

Ditlev Brodersen's research group at Aarhus University has gained unique insight into how bacteria control the amount of toxin in their cells. The new findings can eventually lead to the development of novel forms of treatment for bacterial infections.

Read more about the results.

New protein involved in the replacement of cell molecules

In collaboration with colleagues from La Trobe University, Australia, scientists at Aarhus University have discovered and defined a novel enzyme involved in the replacement and renewal of cell molecules. The enzyme exerts its function within the so-called mitochondria - small “enclosed” compartments in the human cell - where most cellular energy is produced. The findings may ultimately explain the cause of certain diseases with relation to the mitochondria.

New knowledge may lead to the development of future antibiotics

A research team led by Associate Professor Ditlev E. Brodersen, PhD, has revealed the mechanism behind a completely new type of antibiotic, which may have an important impact on the fight against diseases in the future.

Read more about the new research results.

X-rays reveal the self-defence mechanisms of bacteria

En gruppe forskere fra Aarhus Universitet har fået et unikt indblik i, hvordan bakterier styrer mængden af giftstoffer i cellen. De nye resultater vil på sigt muliggøre nye former for behandling af bakterielle infektioner.

Read more about the research results.